| Gene Symbol | CHRM5 |
|---|---|
| Entrez Gene | 1133 |
| Alt Symbol | HM5 |
| Species | Human |
| Gene Type | protein-coding |
| Description | cholinergic receptor, muscarinic 5 |
| Other Description | acetylcholine receptor, muscarinic 5|muscarinic acetylcholine receptor M5 |
| Swissprots | P08912 Q96RG7 |
| Accessions | AAA51569 EAW92282 EAW92283 P08912 AB084282 BAB91222 AF026263 AAB95158 AF385591 AAK68116 AF498919 AAM18942 AK095198 BC041805 AAH41805 BC068528 AAH68528 EU832806 ACE87817 GQ129426 ACT64560 JF432772 ADZ15989 XM_005254141 XP_005254198 XM_011521171 XP_011519473 NM_012125 NP_036257 |
| Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| Top Pathways | Calcium signaling pathway, Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction |