| Gene Symbol |
CHRM5
|
| Entrez Gene |
1133
|
| Alt Symbol |
HM5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, muscarinic 5
|
| Other Description |
acetylcholine receptor, muscarinic 5|muscarinic acetylcholine receptor M5
|
| Swissprots |
P08912 Q96RG7
|
| Accessions |
AAA51569 EAW92282 EAW92283 P08912 AB084282 BAB91222 AF026263 AAB95158 AF385591 AAK68116 AF498919 AAM18942 AK095198 BC041805 AAH41805 BC068528 AAH68528 EU832806 ACE87817 GQ129426 ACT64560 JF432772 ADZ15989 XM_005254141 XP_005254198 XM_011521171 XP_011519473 NM_012125 NP_036257
|
| Function |
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Calcium signaling pathway, Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction
|