Gene Symbol | CHRM5 |
---|---|
Entrez Gene | 1133 |
Alt Symbol | HM5 |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, muscarinic 5 |
Other Description | acetylcholine receptor, muscarinic 5|muscarinic acetylcholine receptor M5 |
Swissprots | P08912 Q96RG7 |
Accessions | AAA51569 EAW92282 EAW92283 P08912 AB084282 BAB91222 AF026263 AAB95158 AF385591 AAK68116 AF498919 AAM18942 AK095198 BC041805 AAH41805 BC068528 AAH68528 EU832806 ACE87817 GQ129426 ACT64560 JF432772 ADZ15989 XM_005254141 XP_005254198 XM_011521171 XP_011519473 NM_012125 NP_036257 |
Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction |
mAChR M5 CRISPR/Cas9 KO Plasmid (h) - sc-402943 from Santa Cruz Biotechnology
|
||||||||
mAChR M5 HDR Plasmid (h) - sc-402943-HDR from Santa Cruz Biotechnology
|
||||||||
mAChR M5 Double Nickase Plasmid (h) - sc-402943-NIC from Santa Cruz Biotechnology
|
||||||||
mAChR M5 Double Nickase Plasmid (h2) - sc-402943-NIC-2 from Santa Cruz Biotechnology
|
||||||||
mAChR M5 CRISPR Activation Plasmid (h) - sc-402943-ACT from Santa Cruz Biotechnology
|
||||||||
mAChR M5 CRISPR Activation Plasmid (h2) - sc-402943-ACT-2 from Santa Cruz Biotechnology
|
||||||||
mAChR M5 Lentiviral Activation Particles (h) - sc-402943-LAC from Santa Cruz Biotechnology
|
||||||||
mAChR M5 Lentiviral Activation Particles (h2) - sc-402943-LAC-2 from Santa Cruz Biotechnology
|
||||||||
mAChR M5 siRNA (h) - sc-42028 from Santa Cruz Biotechnology
|
||||||||
mAChR M5 shRNA Plasmid (h) - sc-42028-SH from Santa Cruz Biotechnology
|
||||||||
mAChR M5 shRNA (h) Lentiviral Particles - sc-42028-V from Santa Cruz Biotechnology
|
||||||||
Muscarinic Acetylcholine Receptor M5/CHRM5 RNAi - H00001133-R02 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU130281 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN6095 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6095 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR06533 from Sigma-Aldrich
|
||||||||
CHRM5 siRNA (Human) - CRH0810 from Cohesion Biosciences
|
||||||||
CHRM5 - MBS8222859 from MyBioSource
|
||||||||
mAChR M5 CRISPR/Cas9 KO Plasmid (h2) - sc-402943-KO-2 from Santa Cruz Biotechnology
|
||||||||
mAChR M5 HDR Plasmid (h2) - sc-402943-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human CHRM5 siRNA - orb261312 from Biorbyt
|
||||||||
CHRM5 shRNA Plasmid (Human) - CHH0810 from Cohesion Biosciences
|