Gene Symbol |
ARHGAP1
|
Entrez Gene |
392
|
Alt Symbol |
CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
Rho GTPase activating protein 1
|
Other Description |
CDC42 GTPase-activating protein|GTPase-activating protein rhoGAP|GTPase-activating protein rhoOGAP|GTPase-activating protein, Rho, 1|rho GTPase-activating protein 1|rho-related small GTPase protein activator|rho-type GTPase-activating protein 1
|
Swissprots |
D3DQQ6 Q07960
|
Accessions |
EAW67982 EAW67983 EAW67984 Q07960 AI640658 AK126404 AK298562 BAG60756 AK307296 AK310605 BC018118 AAH18118 DQ894145 ABM85071 HY004921 U02570 AAA16142 U62794 AAB66594 Z23024 CAA80560 XM_011520094 XP_011518396 XM_011520095 XP_011518397 NM_004308 NP_004299
|
Function |
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.
|
Subcellular Location |
Cytoplasm.
|
Tissue Specificity |
Ubiquitous.
|