Gene Symbol | ARHGAP1 |
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Entrez Gene | 392 |
Alt Symbol | CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP |
Species | Human |
Gene Type | protein-coding |
Description | Rho GTPase activating protein 1 |
Other Description | CDC42 GTPase-activating protein|GTPase-activating protein rhoGAP|GTPase-activating protein rhoOGAP|GTPase-activating protein, Rho, 1|rho GTPase-activating protein 1|rho-related small GTPase protein activator|rho-type GTPase-activating protein 1 |
Swissprots | D3DQQ6 Q07960 |
Accessions | EAW67982 EAW67983 EAW67984 Q07960 AI640658 AK126404 AK298562 BAG60756 AK307296 AK310605 BC018118 AAH18118 DQ894145 ABM85071 HY004921 U02570 AAA16142 U62794 AAB66594 Z23024 CAA80560 XM_011520094 XP_011518396 XM_011520095 XP_011518397 NM_004308 NP_004299 |
Function | GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Ubiquitous. |
ARHGAP1 CRISPR/Cas9 KO Plasmid (h) - sc-407469 from Santa Cruz Biotechnology
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ARHGAP1 HDR Plasmid (h) - sc-407469-HDR from Santa Cruz Biotechnology
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ARHGAP1 Double Nickase Plasmid (h) - sc-407469-NIC from Santa Cruz Biotechnology
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ARHGAP1 Double Nickase Plasmid (h2) - sc-407469-NIC-2 from Santa Cruz Biotechnology
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ARHGAP1 CRISPR Activation Plasmid (h) - sc-407469-ACT from Santa Cruz Biotechnology
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ARHGAP1 CRISPR Activation Plasmid (h2) - sc-407469-ACT-2 from Santa Cruz Biotechnology
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ARHGAP1 Lentiviral Activation Particles (h) - sc-407469-LAC from Santa Cruz Biotechnology
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ARHGAP1 Lentiviral Activation Particles (h2) - sc-407469-LAC-2 from Santa Cruz Biotechnology
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ARHGAP1 siRNA (h) - sc-96477 from Santa Cruz Biotechnology
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ARHGAP1 shRNA Plasmid (h) - sc-96477-SH from Santa Cruz Biotechnology
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ARHGAP1 shRNA (h) Lentiviral Particles - sc-96477-V from Santa Cruz Biotechnology
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ARHGAP1 RNAi - H00000392-R01 from Novus Biologicals
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MISSION® esiRNA - EHU018101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3405 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3405 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10926 from Sigma-Aldrich
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ARHGAP1 siRNA (Human) - CRH0281 from Cohesion Biosciences
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ARHGAP1 - MBS8228510 from MyBioSource
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shRNA set against Human ARHGAP1 (NM_004308.3) - SHH239282 from Creative biogene
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Human ARHGAP1 siRNA - orb260783 from Biorbyt
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ARHGAP1 shRNA Plasmid (Human) - CHH0281 from Cohesion Biosciences
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ARHGAP1 miRNA 3'UTR clone - MiUTR3H-05273 from Creative biogene
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