PLEKHB1

Gene Symbol PLEKHB1
Entrez Gene 58473
Alt Symbol KPL1, PHR1, PHRET1
Species Human
Gene Type protein-coding
Description pleckstrin homology domain containing, family B (evectins) member 1
Other Description PH domain containing protein in retina 1|PH domain containing, retinal 1|PH domain-containing family B member 1|PH domain-containing protein in retina 1|evectin-1|pleckstrin homology domain retinal protein 1|pleckstrin homology domain-containing family B member 1
Swissprots A8K0Q5 B7Z716 Q9UI44 B2RBP1 Q9UI37 Q9UBF5 Q9UF11
Accessions AAG13807 EAW74900 EAW74901 EAW74902 EAW74903 EAW74904 EAW74905 EAW74906 Q9UF11 AB209716 BAD92953 AF081583 AAF21786 AF093249 AAF16684 AF100612 AAF18932 AF101054 AAF18572 AK054725 BAG51417 AK289620 BAF82309 AK289909 BAF82598 AK290109 BAF82798 AK296033 BAH12242 AK301299 BAH13452 AK311158 AK314748 BAG37288 AL712105 BC008075 AAH08075 CK819503 DC305763 EB387039 JF432611 ADZ15828 U89715 AAF16675 XM_011545192 XP_011543494 XM_011545193 XP_011543495 XM_011545194 XP_011543496 NM_001130033 NP_001123505 NM_001130034 NP_001123506 NM_001130035 NP_001123507 NM_001130036 NP_001123508 NM_021200 NP_067023
Function Required for proper localization of retinogeniculate projections but not for eye-specific segregation. {ECO:0000250}.
Subcellular Location Membrane {ECO:0000269|PubMed:10585447}. Cytoplasm {ECO:0000250}. Note=Localizes to the apical juxta- nuclear Golgi region of the cytoplasm (By similarity). Membrane- associated. Highly expressed in the outer segments of photoreceptor cells, both in rods and cones. {ECO:0000250}.
Tissue Specificity Highly expressed in retina and brain. Levels are very low or not detectable in all other tissues tested. {ECO:0000269|PubMed:10585447}.

PLEKHB1-Over-expression-Lysate - LY14352a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag PLEKHB1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PLEKHB1 gene.

PLEKHB1/PHR1 Overexpression Lysate (Native) - NBP2-06551 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: PLEKHB1/PHR1 Overexpression Lysate (Adult Normal) [NBP2-06551] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PLEKHB1/PHR1.

Panoply™ Human PLEKHB1 Knockdown Stable Cell Line - CSC-DC011929 from Creative biogene

Category Cell Line
Species Human
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