Gene Symbol | RNF182 |
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Entrez Gene | 221687 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ring finger protein 182 |
Other Description | E3 ubiquitin-protein ligase RNF182 |
Swissprots | Q8NBG3 B2RDG2 Q8N6D2 |
Accessions | EAW55349 EAW55350 Q8N6D2 AK090576 BAC03481 AK098091 AK315528 BAG37909 AW731636 BC030666 AAH30666 BC050030 AAH50030 DA123125 DA803766 DB094450 DB176198 DQ892438 ABM83364 DQ892444 ABM83370 DQ895648 ABM86574 DQ895649 ABM86575 NM_001165032 NP_001158504 NM_001165033 NP_001158505 NM_001165034 NP_001158506 NM_152737 NP_689950 |
Function | E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway. {ECO:0000269|PubMed:18298843}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:18298843}. |
Tissue Specificity | Up-regulated in neuronal cells subjected to cell death-inducing injuries, such as oxygen and glucose deprivation (at protein level). Could be up-regulated in Alzheimer disease brains. {ECO:0000269|PubMed:18298843}. |
RNF182 CRISPR/Cas9 KO Plasmid (h) - sc-415138 from Santa Cruz Biotechnology
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RNF182 HDR Plasmid (h) - sc-415138-HDR from Santa Cruz Biotechnology
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RNF182 Double Nickase Plasmid (h) - sc-415138-NIC from Santa Cruz Biotechnology
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RNF182 Double Nickase Plasmid (h2) - sc-415138-NIC-2 from Santa Cruz Biotechnology
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RNF182 CRISPR Activation Plasmid (h) - sc-415138-ACT from Santa Cruz Biotechnology
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RNF182 CRISPR Activation Plasmid (h2) - sc-415138-ACT-2 from Santa Cruz Biotechnology
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RNF182 Lentiviral Activation Particles (h) - sc-415138-LAC from Santa Cruz Biotechnology
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RNF182 Lentiviral Activation Particles (h2) - sc-415138-LAC-2 from Santa Cruz Biotechnology
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RNF182 siRNA (h) - sc-95222 from Santa Cruz Biotechnology
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RNF182 shRNA Plasmid (h) - sc-95222-SH from Santa Cruz Biotechnology
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RNF182 shRNA (h) Lentiviral Particles - sc-95222-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU091971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18407 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18407 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11075 from Sigma-Aldrich
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RNF182 siRNA (Human) - CRJ6531 from Cohesion Biosciences
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RNF182 RNAi - H00221687-R01 from Novus Biologicals
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RNF182 - MBS8211131 from MyBioSource
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Human RNF182 siRNA - orb277032 from Biorbyt
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RNF182 shRNA Plasmid (Human) - CHJ6531 from Cohesion Biosciences
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