CLTC

Gene Symbol	CLTC
Entrez Gene	1213
Alt Symbol	CHC, CHC17, CLH-17, CLTCL2, Hc
Species	Human
Gene Type	protein-coding
Description	clathrin, heavy chain (Hc)
Other Description	clathrin heavy chain 1|clathrin heavy chain on chromosome 17|clathrin, heavy polypeptide (Hc)|clathrin, heavy polypeptide-like 2
Swissprots	Q86TF2 Q6N0A0 D3DU00 Q00610
Accessions	EAW94395 EAW94396 EAW94397 EAW94398 EAW94399 Q00610 AB073891 AK127134 BC015854 BC036430 AAH36430 BC051800 AAH51800 BC054489 AAH54489 BX473803 BX640615 CAE45761 D21260 BAA04801 DA248028 X55878 CAA39363 XM_005257012 XP_005257069 XM_011524279 XP_011522581 XM_011524280 XP_011522582 XM_011524281 XP_011522583 NM_001288653 NP_001275582 NM_004859 NP_004850
Function	Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
Subcellular Location	Cytoplasmic vesicle membrane {ECO:0000269|PubMed:17081065}; Peripheral membrane protein {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Membrane, coated pit {ECO:0000269|PubMed:17081065}; Peripheral membrane protein {ECO:0000269|PubMed:17081065}; Cytoplasmic side {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Top Pathways	Huntington's disease, Endocytosis, Lysosome, Bacterial invasion of epithelial cells, Endocrine and other factor-regulated calcium reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human Clathrin heavy chain peptide - ab23440 from Abcam Category Peptide

Human Clathrin heavy chain protein fragment - ab112271 from Abcam Category Protein Source Wheat germ Species Human

CLTC / Clathrin Heavy Chain Antibody Blocking Peptide - LS-E8040 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLTC / Clathrin Heavy Chain Antibody Blocking Peptide - LS-E27044 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Clathrin Heavy Chain 1/CHC17 Protein - H00001213-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CLTC-Antibody-Center-Blocking-peptide - BP5911c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Clathrin heavy chain - H00001213-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Clathrin heavy chain - H00001213-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CLTC fusion protein - ag5568 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CLTC fusion protein - Ag5470 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human CLTC - CLTC-26707TH from Creative Biomart Category Protein Source Wheat germ

CLTC Peptide - abx164838 from Abbexa Category Peptide Species Human, Mouse, Rat

CLTC fusion protein - Ag25040 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET30a Species Human

CLTC fusion protein - Ag25041 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

Clathrin Heavy Chain 1/CHC17 Recombinant Protein Antigen - NBP2-49293PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

CLTC Peptide, Human - M34GP03324H from Creative Peptides Category Peptide Source Synthetic. Species Human

Ubiquitin scaffold protein anti-Human HC - SUB-L206 from Creative Biolabs Category Protein Source E. coli Species Human

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