| Gene Symbol |
CCL3L1
|
| Entrez Gene |
6349
|
| Alt Symbol |
464.2, D17S1718, G0S19-2, LD78, LD78-beta(1-70), LD78BETA, MIP1AP, SCYA3L, SCYA3L1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chemokine (C-C motif) ligand 3-like 1
|
| Other Description |
C-C motif chemokine 3-like 1|G0/G1 switch regulatory protein 19-2|small inducible cytokine A3-like 1|tonsillar lymphocyte LD78 beta protein
|
| Swissprots |
B2RUX4 A6NGK6 Q53YA5 Q3B7A8 P16619 Q96I68
|
| Accessions |
AAA35859 BAA14173 P16619 AA362164 AV739733 BC027888 AAH27888 BC107710 AAI07711 BC146914 AAI46915 X52149 CAA36397 NM_021006 NP_066286 NR_111964
|
| Function |
Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1- infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. {ECO:0000269|PubMed:10961862, ECO:0000269|PubMed:11449371}.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, Chemokine signaling pathway, Chagas disease (American trypanosomiasis), Rheumatoid arthritis
|