Gene Symbol | CCL3L1 |
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Entrez Gene | 6349 |
Alt Symbol | 464.2, D17S1718, G0S19-2, LD78, LD78-beta(1-70), LD78BETA, MIP1AP, SCYA3L, SCYA3L1 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 3-like 1 |
Other Description | C-C motif chemokine 3-like 1|G0/G1 switch regulatory protein 19-2|small inducible cytokine A3-like 1|tonsillar lymphocyte LD78 beta protein |
Swissprots | B2RUX4 A6NGK6 Q53YA5 Q3B7A8 P16619 Q96I68 |
Accessions | AAA35859 BAA14173 P16619 AA362164 AV739733 BC027888 AAH27888 BC107710 AAI07711 BC146914 AAI46915 X52149 CAA36397 NM_021006 NP_066286 NR_111964 |
Function | Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1- infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. {ECO:0000269|PubMed:10961862, ECO:0000269|PubMed:11449371}. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, Chemokine signaling pathway, Chagas disease (American trypanosomiasis), Rheumatoid arthritis |
MIP-1α CRISPR/Cas9 KO Plasmid (h) - sc-416949 from Santa Cruz Biotechnology
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MIP-1α HDR Plasmid (h) - sc-416949-HDR from Santa Cruz Biotechnology
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MIP-1α Double Nickase Plasmid (h) - sc-416949-NIC from Santa Cruz Biotechnology
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MIP-1α Double Nickase Plasmid (h2) - sc-416949-NIC-2 from Santa Cruz Biotechnology
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MIP-1α CRISPR Activation Plasmid (h) - sc-416949-ACT from Santa Cruz Biotechnology
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MIP-1α CRISPR Activation Plasmid (h2) - sc-416949-ACT-2 from Santa Cruz Biotechnology
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MIP-1α Lentiviral Activation Particles (h) - sc-416949-LAC from Santa Cruz Biotechnology
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MIP-1α Lentiviral Activation Particles (h2) - sc-416949-LAC-2 from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN5616 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5616 from Sigma-Aldrich
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CCL3L1 siRNA (Human) - CRH4284 from Cohesion Biosciences
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shRNA set against Human CCL3L1 (NM_021006.4) - SHH257669 from Creative biogene
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Human CCL3L1 siRNA - orb264786 from Biorbyt
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CCL3L1 shRNA Plasmid (Human) - CHH4284 from Cohesion Biosciences
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CCL3L1 miRNA 3'UTR clone - MiUTR1H-01804 from Creative biogene
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