| Gene Symbol |
XPNPEP2
|
| Entrez Gene |
7512
|
| Alt Symbol |
AEACEI, APP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
|
| Other Description |
X-Pro aminopeptidase 2|aminoacylproline aminopeptidase|mAmP|membrane-bound APP|membrane-bound AmP|membrane-bound aminopeptidase P|xaa-Pro aminopeptidase 2
|
| Swissprots |
O43895 A0AV16 O75994
|
| Accessions |
AAG28480 EAX11827 O43895 AF086417 AK300954 BAG62582 BC126174 AAI26175 BC143901 AAI43902 BF830085 BP270314 BQ224207 BX386512 CD617070 U90724 AAB96394 NM_003399 NP_003390
|
| Function |
A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin.
|
| Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor.
|
| Tissue Specificity |
Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary.
|
| Top Pathways |
Protein digestion and absorption
|
![Western Blot: XPNPEP2 Overexpression Lysate (Adult Normal) [NBL1-17909] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for XPNPEP2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8901_XPNPEP2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-17909-img0002.jpg)