Gene Symbol | XPNPEP2 |
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Entrez Gene | 7512 |
Alt Symbol | AEACEI, APP2 |
Species | Human |
Gene Type | protein-coding |
Description | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
Other Description | X-Pro aminopeptidase 2|aminoacylproline aminopeptidase|mAmP|membrane-bound APP|membrane-bound AmP|membrane-bound aminopeptidase P|xaa-Pro aminopeptidase 2 |
Swissprots | O43895 A0AV16 O75994 |
Accessions | AAG28480 EAX11827 O43895 AF086417 AK300954 BAG62582 BC126174 AAI26175 BC143901 AAI43902 BF830085 BP270314 BQ224207 BX386512 CD617070 U90724 AAB96394 NM_003399 NP_003390 |
Function | A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary. |
Top Pathways | Protein digestion and absorption |
Aminopeptidase P2 CRISPR/Cas9 KO Plasmid (h) - sc-407476 from Santa Cruz Biotechnology
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Aminopeptidase P2 HDR Plasmid (h) - sc-407476-HDR from Santa Cruz Biotechnology
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Aminopeptidase P2 Double Nickase Plasmid (h) - sc-407476-NIC from Santa Cruz Biotechnology
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Aminopeptidase P2 Double Nickase Plasmid (h2) - sc-407476-NIC-2 from Santa Cruz Biotechnology
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Aminopeptidase P2 CRISPR Activation Plasmid (h) - sc-407476-ACT from Santa Cruz Biotechnology
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Aminopeptidase P2 CRISPR Activation Plasmid (h2) - sc-407476-ACT-2 from Santa Cruz Biotechnology
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Aminopeptidase P2 Lentiviral Activation Particles (h) - sc-407476-LAC from Santa Cruz Biotechnology
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Aminopeptidase P2 Lentiviral Activation Particles (h2) - sc-407476-LAC-2 from Santa Cruz Biotechnology
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Aminopeptidase P2 siRNA (h) - sc-72488 from Santa Cruz Biotechnology
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Aminopeptidase P2 shRNA Plasmid (h) - sc-72488-SH from Santa Cruz Biotechnology
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Aminopeptidase P2 shRNA (h) Lentiviral Particles - sc-72488-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU150571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22975 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22975 from Sigma-Aldrich
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XPNPEP2 siRNA (Human) - CRH5134 from Cohesion Biosciences
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Aminopeptidase P2/XPNPEP2 RNAi - H00007512-R01 from Novus Biologicals
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XPNPEP2 - MBS8230077 from MyBioSource
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shRNA set against Human XPNPEP2 (NM_003399.5) - SHH447976 from Creative biogene
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shRNA set against Human XPNPEP2(NM_003399.5) - SHL138386 from Creative biogene
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Human XPNPEP2 siRNA - orb265636 from Biorbyt
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XPNPEP2 shRNA Plasmid (Human) - CHH5134 from Cohesion Biosciences
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XPNPEP2 miRNA 3'UTR clone - MiUTR3H-02596 from Creative biogene
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