Gene Symbol | ESCO2 |
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Entrez Gene | 157570 |
Alt Symbol | 2410004I17Rik, EFO2, RBS |
Species | Human |
Gene Type | protein-coding |
Description | establishment of sister chromatid cohesion N-acetyltransferase 2 |
Other Description | ECO1 homolog 2|N-acetyltransferase ESCO2 |
Swissprots | Q56NI9 B3KW59 Q49AP4 |
Accessions | EAW63538 Q56NI9 AF306675 AF306676 AF306677 AF306678 AF306679 AK124215 BAG54021 AL832666 AY882862 AAX68677 BC017933 BC034641 AAH34641 BC040615 BC141418 AAI41419 BC146562 AAI46563 XM_011544421 XP_011542723 XM_011544422 XP_011542724 XR_949378 XR_949379 NM_001017420 NP_001017420 |
Function | Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3. {ECO:0000269|PubMed:15821733, ECO:0000269|PubMed:19907496, ECO:0000269|PubMed:21111234}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:19907496}. Chromosome {ECO:0000269|PubMed:19907496}. |
Tissue Specificity | Widely expressed in fetal tissues. In adult, it is expressed in thymus, placenta and small intestine. {ECO:0000269|PubMed:15821733}. |
Human ESCO2 full length protein - ab165689 from Abcam
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ESCO2 Antibody Blocking Peptide - LS-E436 from LifeSpan Bioscience
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Recombinant Human ESCO2 Protein - H00157570-P01 from Novus Biologicals
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ESCO2-Antibody-Center-Blocking-peptide - BP10717c from Abgent, a WuXi AppTec company
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ESCO2 - H00157570-P01 from Acris Antibodies
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ESCO2 fusion protein - ag18893 from Proteintech Group
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ESCO2 fusion protein - ag18807 from Proteintech Group
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Recombinant Human ESCO2, GST-tagged - ESCO2-01H from Creative Biomart
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Recombinant Human N-acetyltransferase ESCO2(ESCO2) - CSB-YP710073HU CSB-EP710073HU CSB-BP710073HU CSB-MP710073HU from Cusabio
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ESCO2 Peptide, Human - M34GP05075H from Creative Peptides
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ESCO2 Recombinant Protein Antigen - NBP2-58532PEP from Novus Biologicals
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ESCO2 Recombinant Protein Antigen - NBP2-55577PEP from Novus Biologicals
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N-acetyltransferase ESCO2 (ESCO2), Recombinant Protein - MBS1327183 from MyBioSource
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