TRAF5

Gene Symbol TRAF5
Entrez Gene 7188
Alt Symbol MGC:39780, RNF84
Species Human
Gene Type protein-coding
Description TNF receptor-associated factor 5
Other Description RING finger protein 84
Swissprots Q6FHY1 B4E0A2 B4DIS9 O00463
Accessions EAW93419 EAW93420 EAW93421 EAW93422 O00463 AB000509 BAA25262 AK126502 BAG54338 AK295766 BAG58591 AK303286 BAG64364 BC029600 AAH29600 BC032830 BM453281 BU676629 CD709275 CR536557 CAG38794 DB218840 DB290838 GQ129370 ACT64504 GQ129371 ACT64505 U69108 AAC51329 XM_011509956 XP_011508258 XM_011509957 XP_011508259 XM_011509958 XP_011508260 XM_011509959 XP_011508261 XM_011509960 XP_011508262 NM_001033910 NP_001029082 NM_004619 NP_004610 NM_145759 NP_665702
Function Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. {ECO:0000269|PubMed:15121867}.
Subcellular Location Cytoplasm {ECO:0000305|PubMed:15121867}. Cytoplasm, cytosol {ECO:0000269|PubMed:15121867}.
Tissue Specificity Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
Top Pathways Small cell lung cancer, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection, TNF signaling pathway

TRAF5 CRISPR/Cas9 KO Plasmid (h) - sc-402073 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 HDR Plasmid (h) - sc-402073-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 Double Nickase Plasmid (h) - sc-402073-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 Double Nickase Plasmid (h2) - sc-402073-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 CRISPR Activation Plasmid (h) - sc-402073-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 CRISPR Activation Plasmid (h2) - sc-402073-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 Lentiviral Activation Particles (h) - sc-402073-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 Lentiviral Activation Particles (h2) - sc-402073-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRAF5 siRNA (h) - sc-36715 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRAF5 shRNA Plasmid (h) - sc-36715-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRAF5 shRNA (h) Lentiviral Particles - sc-36715-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRAF-5 RNAi - H00007188-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TRAF-5 RNAi - H00007188-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TRAF-5 RNAi - H00007188-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU060831 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21910 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21910 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13229 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13229

TRAF5 siRNA (Human) - CRH4937 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRAF5 - MBS8213159 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRAF5 (NM_004619.3) - SHH433764 from Creative biogene

Category siRNA
Species Reactivities Human

SignalSilence ® TRAF5 siRNA I - 38805 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from A172 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® TRAF5 siRNA I (+), or SignalSilence ® TRAF5 siRNA II #60131 using TRAF5 (D3E2R) Rabbit mAb #41658 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The TRAF5 (D3E2R) Rabbit mAb confirms silencing of TRAF5 expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

SignalSilence ® TRAF5 siRNA II - 60131 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from A-172 cells, transfected with 100 nM SignalSilence® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® TRAF5 siRNA I #38805 (+), or SignalSilence ® TRAF5 siRNA II using TRAF5 (D3E2R) Rabbit mAb #41658 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The TRAF5 (D3E2R) Rabbit mAb confirms silencing of TRAF5 expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

Human TRAF5 siRNA - orb265439 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRAF5 shRNA Plasmid (Human) - CHH4937 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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