| Gene Symbol | PDHA2 |
|---|---|
| Entrez Gene | 5161 |
| Alt Symbol | PDHAL |
| Species | Human |
| Gene Type | protein-coding |
| Description | pyruvate dehydrogenase (lipoamide) alpha 2 |
| Other Description | PDHE1-A type II|pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial|pyruvate dehydrogenase, E1-alpha polypeptide, testis specific |
| Swissprots | Q6NXQ1 P29803 Q4VC02 Q0VDI5 B2R9Q3 |
| Accessions | AAA60232 AAF14652 CBH19409 CBH30590 EAX06063 P29803 AK313872 BAG36600 BC030697 AAH30697 BC066953 AAH66953 BC094760 AAH94760 BC119656 AAI19657 BC119657 AAI19658 BC127637 AAI27638 BC127638 AAI27639 NM_005390 NP_005381 |
| Function | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. {ECO:0000269|PubMed:16436377}. |
| Subcellular Location | Mitochondrion matrix. |
| Tissue Specificity | Testis. Expressed in postmeiotic spermatogenic cells. {ECO:0000269|PubMed:22750801}. |
| Top Pathways | Glycolysis / Gluconeogenesis, Citrate cycle (TCA cycle), Central carbon metabolism in cancer, Glucagon signaling pathway, Pyruvate metabolism |