| Gene Symbol |
PDHA2
|
| Entrez Gene |
5161
|
| Alt Symbol |
PDHAL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pyruvate dehydrogenase (lipoamide) alpha 2
|
| Other Description |
PDHE1-A type II|pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial|pyruvate dehydrogenase, E1-alpha polypeptide, testis specific
|
| Swissprots |
Q6NXQ1 P29803 Q4VC02 Q0VDI5 B2R9Q3
|
| Accessions |
AAA60232 AAF14652 CBH19409 CBH30590 EAX06063 P29803 AK313872 BAG36600 BC030697 AAH30697 BC066953 AAH66953 BC094760 AAH94760 BC119656 AAI19657 BC119657 AAI19658 BC127637 AAI27638 BC127638 AAI27639 NM_005390 NP_005381
|
| Function |
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. {ECO:0000269|PubMed:16436377}.
|
| Subcellular Location |
Mitochondrion matrix.
|
| Tissue Specificity |
Testis. Expressed in postmeiotic spermatogenic cells. {ECO:0000269|PubMed:22750801}.
|
| Top Pathways |
Glycolysis / Gluconeogenesis, Citrate cycle (TCA cycle), Central carbon metabolism in cancer, Glucagon signaling pathway, Pyruvate metabolism
|