MAP4K3

Gene Symbol MAP4K3
Entrez Gene 8491
Alt Symbol GLK, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase kinase kinase 3
Other Description MAPK/ERK kinase kinase kinase 3|MEK kinase kinase 3|germinal center kinase-like kinase|germinal center kinase-related protein kinase
Swissprots Q9Y6R5 Q9UDM5 Q8IVH8 Q8IVH7 Q6IQ39
Accessions AAF19240 AAN75849 AAN75850 AAY14734 EAX00346 EAX00347 Q8IVH8 AK021553 BAG51037 AK291467 BAF84156 AK299889 BAG61735 AK314487 AK316144 BAH14515 BC060880 BC071579 AAH71579 DA409370 EU832785 ACE87796 GQ129258 ACT64392 XR_939730 NM_001270425 NP_001257354 NM_003618 NP_003609
Function May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. {ECO:0000269|PubMed:9275185}.
Tissue Specificity Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver. {ECO:0000269|PubMed:9275185}.
Top Pathways MAPK signaling pathway

GLK CRISPR/Cas9 KO Plasmid (h) - sc-406054 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK HDR Plasmid (h) - sc-406054-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK Double Nickase Plasmid (h) - sc-406054-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK Double Nickase Plasmid (h2) - sc-406054-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK CRISPR Activation Plasmid (h) - sc-406054-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK CRISPR Activation Plasmid (h2) - sc-406054-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK Lentiviral Activation Particles (h) - sc-406054-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK Lentiviral Activation Particles (h2) - sc-406054-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GLK siRNA (h) - sc-39241 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GLK shRNA Plasmid (h) - sc-39241-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GLK shRNA (h) Lentiviral Particles - sc-39241-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MAP4K3 RNAi - H00008491-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU071911 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1174 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1175 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1176 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2165 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2165 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09093 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09093

MAP4K3 siRNA (Human) - CRH5566 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MAP4K3 (NM_003618.3) - SHH337823 from Creative biogene

Category siRNA
Species Reactivities Human

MAP4K3 shRNA Plasmid (Human) - CHH5566 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MAP4K3 miRNA 3'UTR clone - MiUTR3H-07208 from Creative biogene

Species Reactivities Human
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