KIF16B

Gene Symbol	KIF16B
Entrez Gene	55614
Alt Symbol	C20orf23, KISC20ORF, SNX23
Species	Human
Gene Type	protein-coding
Description	kinesin family member 16B
Other Description	kinesin motor protein\|kinesin-like protein KIF16B\|sorting nexin 23
Swissprots	B1AKG3 Q9BQM5 Q8IYU0 B1AKT7 Q2TBF5 Q9BQJ8 Q9H5U0 Q5HYC0 C9JSM8 C9JDN5 Q86VL9 A6NKJ9 C9JWJ7 Q5HYK1 Q5JWW3 Q9BQM0 C9JI52 Q9HCI2 Q86YS5 Q9NXN9 Q9BQM1 A7E2A8 Q96L93 Q5TFK5
Accessions	EAX10287 EAX10288 EAX10289 EAX10290 Q96L93 AB046810 BAB13416 AK000142 BAA90971 AK026698 BAB15530 AK095322 AK307399 AY044654 AAK98768 AY166853 AAO17292 BC015384 BC034984 AAH34984 BC050577 BC110317 AAI10318 BC150261 AAI50262 BQ067573 BX647572 CAI46105 BX648426 CAI46266 XM_005260750 XP_005260807 XM_005260751 XP_005260808 XM_005260752 XP_005260809 XM_005260753 XP_005260810 XM_005260754 XP_005260811 XM_005260755 XP_005260812 XM_006723588 XP_006723651 XM_011529288 XP_011527590 NM_001199865 NP_001186794 NM_001199866 NP_001186795 NM_024704 NP_078980
Function	Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. {ECO:0000269\|PubMed:15882625}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000305}. Early endosome membrane. Note=It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14.
Tissue Specificity	Primarily expressed in brain. Also present in kidney, liver, intestine, placenta, leukocytes, heart and skeletal muscle (at protein level). {ECO:0000269\|PubMed:15882625}.

KIF16B (H-270) - sc-67372 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

KIF16B (N-14) - sc-50992 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

KIF16B (H-6) - sc-390309 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

KIF16B (H-6): sc-390309. Western blot analysis of KIF16B expression in human liver (A), human placenta (B), human heart (C) and human skeletal muscle (D) tissue extracts.

KIF16B (E-13) - sc-50991 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

KIF16B (E-13): sc-50991. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes and cytoplasmic and membrane staining of endothelial cells.

Anti-KIF16B antibody - ab67790 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-KIF16B antibody (ab67790) at 1/500 dilutionLane 1 : KIF16B transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-KIF16B Antibody (aa10-40, AP) - LS-C261131 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KIF16B Antibody (aa10-40, APC) - LS-C261132 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KIF16B Antibody (aa10-40, Biotin) - LS-C261133 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KIF16B Antibody (aa10-40, FITC) - LS-C261134 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KIF16B Antibody (aa10-40, Azide-free, HRP) - LS-C261135 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KIF16B Antibody (aa10-40, PE) - LS-C261136 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KIF16B Antibody (aa10-40) - LS-C329726 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-KIF16B Antibody (aa65-175) - LS-C308640 from LifeSpan Bioscience

Prices	$455.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-KIF16B Antibody - LS-C308639 from LifeSpan Bioscience

Prices	$455.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Anti-KIF16B Antibody (aa55-104) - LS-C201290 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Human 293T. KIF16B antibody dilution 1.0 ug/ml.

Anti-KIF16B Antibody (aa1-30) - LS-C165512 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

KIF16b Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

KIF16B Antibody - NBP2-14157 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemistry-Paraffin: KIF16B Antibody [NBP2-14157] - Staining of human kidney shows strong cytoplasmic positivity in cells of tubules.

KIF16B Antibody - 26520002 from Novus Biologicals

Prices	$329.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

KIF16B Antibody - H00055614-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

Western Blot: KIF16B Antibody [H00055614-B01P] - Analysis of KIF16B expression in transfected 293T cell line by KIF16B polyclonal antibody. Lane 1: C20orf23 transfected lysate(144.87 KDa). Lane 2: Non-transfected lysate.

KIF16B Antibody (2B5) - H00055614-M05 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2B5

Sandwich ELISA: KIF16B Antibody (2B5) [H00055614-M05] - Detection limit for recombinant GST tagged KIF16B is 0.3 ng/ml as a capture antibody.

Monoclonal Anti-KIF16B antibody produced in mouse - SAB1401759 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	2B5

<B>Immunoblotting</B><BR/>Monoclonal Anti-KIF16B, antibody produced in mouse, clone 2B5, purified immunoglobulin: <B>Cat. No. SAB1401759</B>: Antibody concentration: 1.0 μg/mL. Specific band of ~38.21 kDa using immunogen protein lysate.

Anti-C20ORF23 antibody produced in mouse - SAB1407678 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-C20orf23: <B>Cat. No. SAB1407678</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~144.9 kDa using KIF16B transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-KIF16B antibody produced in rabbit - HPA051198 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-KIF16B:<B>Cat. No. HPA051198</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells of tubules.

KIF16B Antibody - N-terminal region (ARP34078_P050) - ARP34078_P050 from Aviva Systems Biology

Prices	$289.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

KIF16b-Antibody - AP15010a from Abgent, a WuXi AppTec company

Prices	$99.00, $295.00
Sizes	80 µl, 400 µl
Host	Rabbit
Clonality	Polyclonal

KIF16b Antibody (Cat. #AP15010a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KIF16b antibody detected the KIF16b protein (arrow).

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