SEC14L2

Gene Symbol SEC14L2
Entrez Gene 23541
Alt Symbol C22orf6, SPF, TAP, TAP1
Species Human
Gene Type protein-coding
Description SEC14-like 2 (S. cerevisiae)
Other Description SEC14-like protein 2|alpha-tocopherol-associated protein|squalene transfer protein|supernatant protein factor|tocopherol-associated protein
Swissprots Q53EQ2 F5H3U4 Q9ULN4 Q6PD61 B7Z8Q1 O76054
Accessions AAF19256 EAW59885 EAW59886 EAW59887 EAW59888 O76054 AA610131 AB033012 BAA86500 AK056163 AK091402 BAG52350 AK092576 AK223587 BAD97307 AK296540 BAH12384 AK303751 BAH14037 AK314390 BAG37015 AL096881 CAB51405 AY203959 AAP34482 AY927430 AY927434 AY927435 AY927436 AY927437 AY927438 AY927439 AY927441 BC048337 BC058915 AAH58915 BM680990 BU734336 CR456571 CAG30457 CU013170 CAK54601 CU013458 CAK54900 DC375707 NM_001204204 NP_001191133 NM_001291932 NP_001278861 NM_012429 NP_036561 NM_033382 NP_203740
Function Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
Subcellular Location Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha- tocopherol.
Tissue Specificity Widely expressed. Strong expression in liver, brain and prostate. {ECO:0000269|PubMed:10829015}.

SEC14L2 CRISPR/Cas9 KO Plasmid (h) - sc-406092 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 HDR Plasmid (h) - sc-406092-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 Double Nickase Plasmid (h) - sc-406092-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 Double Nickase Plasmid (h2) - sc-406092-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 CRISPR Activation Plasmid (h) - sc-406092-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 CRISPR Activation Plasmid (h2) - sc-406092-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 Lentiviral Activation Particles (h) - sc-406092-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 Lentiviral Activation Particles (h2) - sc-406092-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SEC14L2 siRNA (h) - sc-44738 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SEC14L2 shRNA Plasmid (h)-SH - sc-44738-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SEC14L2 shRNA (h) Lentiviral Particles - sc-44738-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU146781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19021 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19021 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12667 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr12667

SEC14L2 siRNA (Human) - CRH8343 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SEC14L2 RNAi - H00023541-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SEC14L2 - MBS8239591 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SEC14L2 (NM_012429.3) - SHH403661 from Creative biogene

Category siRNA
Species Reactivities Human

SEC14L2 shRNA Plasmid (Human) - CHH8343 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SEC14L2 miRNA 3'UTR clone - MiUTR3H-09307 from Creative biogene

Species Reactivities Human

SEC14L2 miRNA 3'UTR clone - MiUTR4H-TG12423 from Creative biogene

Species Reactivities Human
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