PTCRA

Gene Symbol PTCRA
Entrez Gene 171558
Alt Symbol PT-ALPHA, PTA
Species Human
Gene Type protein-coding
Description pre T-cell antigen receptor alpha
Other Description pT-alpha-TCR|pre-T-cell receptor alpha chain
Swissprots Q6ISU1 Q5TFZ7
Accessions AAC83346 EAX04107 EAX04108 EAX04109 EAX04110 Q6ISU1 AF101436 AAF21890 AF165312 AAF89556 AK130819 BAC85438 AK303523 BAG64551 AK310559 AK312223 BAG35156 AW014894 BC069336 AAH69336 BC100771 AAI00772 BC100772 AAI00773 BC100773 AAI00774 BC100774 AAI00775 BC153829 AAI53830 U36759 AAB06194 U38996 AAB18373 XM_011514316 XP_011512618 XM_011514317 XP_011512619 NM_001243168 NP_001230097 NM_001243169 NP_001230098 NM_001243170 NP_001230099 NM_138296 NP_612153
Function The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow. {ECO:0000269|PubMed:8618853, ECO:0000269|PubMed:8760805}.
Top Pathways Notch signaling pathway, Transcriptional misregulation in cancer

Pre-TCRα CRISPR/Cas9 KO Plasmid (h) - sc-417210 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα HDR Plasmid (h) - sc-417210-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα Double Nickase Plasmid (h) - sc-417210-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα Double Nickase Plasmid (h2) - sc-417210-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα CRISPR Activation Plasmid (h) - sc-417210-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα CRISPR Activation Plasmid (h2) - sc-417210-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα Lentiviral Activation Particles (h) - sc-417210-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα Lentiviral Activation Particles (h2) - sc-417210-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pre-TCRα siRNA (h) - sc-44040 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pre-TCRα shRNA Plasmid (h) - sc-44040-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pre-TCRα shRNA (h) Lentiviral Particles - sc-44040-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PTCRA RNAi - H00171558-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN17659 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17659 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00422 from Sigma-Aldrich

Category miRNA

PTCRA siRNA (Human) - CRJ6148 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PTCRA (NM_138296.2) - SHH385872 from Creative biogene

Category siRNA
Species Reactivities Human

Human PTCRA siRNA - orb276649 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PTCRA shRNA Plasmid (Human) - CHJ6148 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PTCRA miRNA 3'UTR clone - MiUTR1H-08409 from Creative biogene

Species Reactivities Human
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