| Gene Symbol |
ADGRB3
|
| Entrez Gene |
577
|
| Alt Symbol |
BAI3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adhesion G protein-coupled receptor B3
|
| Other Description |
brain-specific angiogenesis inhibitor 3|dJ91B17.1 (brain-specific angiogenesis inhibitor 3)
|
| Swissprots |
Q9BX54 B7Z1K0 Q5VY37 Q2NKN6 O60297 O60242
|
| Accessions |
EAW48836 EAW48837 O60242 AB005299 BAA25363 AB011122 BAA25476 AK289696 BAF82385 AK293560 BAH11536 AK295516 BAH12092 AK316174 BAH14545 BC111720 AAI11721 CR740925 DB446627 XM_005248752 XP_005248809 XM_006715534 XP_006715597 XM_011536008 XP_011534310 XM_011536009 XP_011534311 XM_011536010 XP_011534312 XM_011536011 XP_011534313 XM_011536012 XP_011534314 XM_011536013 XP_011534315 NM_001704 NP_001695
|
| Function |
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:21262840, ECO:0000269|PubMed:22333914}; Multi-pass membrane protein {ECO:0000269|PubMed:21262840, ECO:0000269|PubMed:22333914}.
|
| Tissue Specificity |
Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines.
|
![Western Blot: BAI3 Overexpression Lysate (Adult Normal) [NBL1-07905] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BAI3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3365_BAI3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07905-img0002.jpg)