Gene Symbol | ADGRB3 |
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Entrez Gene | 577 |
Alt Symbol | BAI3 |
Species | Human |
Gene Type | protein-coding |
Description | adhesion G protein-coupled receptor B3 |
Other Description | brain-specific angiogenesis inhibitor 3|dJ91B17.1 (brain-specific angiogenesis inhibitor 3) |
Swissprots | Q9BX54 B7Z1K0 Q5VY37 Q2NKN6 O60297 O60242 |
Accessions | EAW48836 EAW48837 O60242 AB005299 BAA25363 AB011122 BAA25476 AK289696 BAF82385 AK293560 BAH11536 AK295516 BAH12092 AK316174 BAH14545 BC111720 AAI11721 CR740925 DB446627 XM_005248752 XP_005248809 XM_006715534 XP_006715597 XM_011536008 XP_011534310 XM_011536009 XP_011534311 XM_011536010 XP_011534312 XM_011536011 XP_011534313 XM_011536012 XP_011534314 XM_011536013 XP_011534315 NM_001704 NP_001695 |
Function | May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21262840, ECO:0000269|PubMed:22333914}; Multi-pass membrane protein {ECO:0000269|PubMed:21262840, ECO:0000269|PubMed:22333914}. |
Tissue Specificity | Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines. |
BAI-3 CRISPR/Cas9 KO Plasmid (h) - sc-405498 from Santa Cruz Biotechnology
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BAI-3 HDR Plasmid (h) - sc-405498-HDR from Santa Cruz Biotechnology
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BAI-3 Double Nickase Plasmid (h) - sc-405498-NIC from Santa Cruz Biotechnology
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BAI-3 Double Nickase Plasmid (h2) - sc-405498-NIC-2 from Santa Cruz Biotechnology
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BAI-3 CRISPR Activation Plasmid (h) - sc-405498-ACT from Santa Cruz Biotechnology
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BAI-3 CRISPR Activation Plasmid (h2) - sc-405498-ACT-2 from Santa Cruz Biotechnology
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BAI-3 Lentiviral Activation Particles (h) - sc-405498-LAC from Santa Cruz Biotechnology
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BAI-3 Lentiviral Activation Particles (h2) - sc-405498-LAC-2 from Santa Cruz Biotechnology
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BAI-3 siRNA (h) - sc-45212 from Santa Cruz Biotechnology
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BAI-3 shRNA Plasmid (h) - sc-45212-SH from Santa Cruz Biotechnology
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BAI-3 shRNA (h) Lentiviral Particles - sc-45212-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU002391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3850 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3850 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05329 from Sigma-Aldrich
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BAI3 siRNA (Human) - CRH0395 from Cohesion Biosciences
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BAI3 RNAi - H00000577-R02 from Novus Biologicals
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BAI3 - MBS828020 from MyBioSource
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shRNA set against Human BAI3 (NM_001704.2) - SHH244738 from Creative biogene
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Human BAI3 siRNA - orb260897 from Biorbyt
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BAI3 shRNA Plasmid (Human) - CHH0395 from Cohesion Biosciences
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BAI3 miRNA 3'UTR clone - MiUTR1H-00797 from Creative biogene
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