| Gene Symbol |
GATB
|
| Entrez Gene |
5188
|
| Alt Symbol |
HSPC199, PET112, PET112L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutamyl-tRNA(Gln) amidotransferase, subunit B
|
| Other Description |
PET112 homolog|cytochrome c oxidase assembly factor PET112 homolog|cytochrome oxidase assembly factor PET112 homolog|glu-AdT subunit B|glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial
|
| Swissprots |
Q9P0S6 Q9Y2B8 Q53GP4 Q4W5M8 O75879
|
| Accessions |
AAY40897 EAX04981 EAX04982 EAX04983 O75879 AB019410 AF026851 AAD08640 AF151033 AAF36119 AK124986 AK222887 BAD96607 AK225241 AK303461 BAG64504 AK312957 BAG35796 BC067838 BC130348 AAI30349 BC136547 AAI36548 BP348031 BX537555 CAH56162 XM_005263063 XP_005263120 XM_011532026 XP_011530328 NM_004564 NP_004555
|
| Function |
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). {ECO:0000255|HAMAP-Rule:MF_03147, ECO:0000269|PubMed:19805282}.
|
| Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03147, ECO:0000269|PubMed:9878253}.
|
| Tissue Specificity |
Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle and heart. {ECO:0000269|PubMed:9878253}.
|
| Top Pathways |
Aminoacyl-tRNA biosynthesis
|