Gene Symbol | CROT |
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Entrez Gene | 54677 |
Alt Symbol | COT |
Species | Human |
Gene Type | protein-coding |
Description | carnitine O-octanoyltransferase |
Other Description | peroxisomal carnitine O-octanoyltransferase|peroxisomal carnitine acyltransferase |
Swissprots | Q9Y6I2 A4D1D6 E7EQF2 Q86V17 Q9UKG9 Q8IUW9 |
Accessions | EAL24177 EAW76954 Q9UKG9 AA062685 AF052187 AF073770 AAD41654 AF168793 AAF03234 AK127901 AK300114 BAG61909 AK313487 BC006015 BC012483 BC019226 BC039004 AAH39004 BC051874 AAH51874 DA518578 DA865171 XM_011516337 XP_011514639 NM_001143935 NP_001137407 NM_001243745 NP_001230674 NM_021151 NP_066974 |
Function | Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl- CoA, to its corresponding carnitine ester. {ECO:0000269|PubMed:10486279}. |
Subcellular Location | Peroxisome {ECO:0000305}. |
Top Pathways | Peroxisome |
CROT CRISPR/Cas9 KO Plasmid (h) - sc-412320 from Santa Cruz Biotechnology
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CROT HDR Plasmid (h) - sc-412320-HDR from Santa Cruz Biotechnology
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CROT Double Nickase Plasmid (h) - sc-412320-NIC from Santa Cruz Biotechnology
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CROT Double Nickase Plasmid (h2) - sc-412320-NIC-2 from Santa Cruz Biotechnology
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CROT CRISPR Activation Plasmid (h) - sc-412320-ACT from Santa Cruz Biotechnology
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CROT CRISPR Activation Plasmid (h2) - sc-412320-ACT-2 from Santa Cruz Biotechnology
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CROT Lentiviral Activation Particles (h) - sc-412320-LAC from Santa Cruz Biotechnology
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CROT Lentiviral Activation Particles (h2) - sc-412320-LAC-2 from Santa Cruz Biotechnology
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CROT siRNA (h) - sc-89588 from Santa Cruz Biotechnology
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CROT shRNA Plasmid (h) - sc-89588-SH from Santa Cruz Biotechnology
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CROT shRNA (h) Lentiviral Particles - sc-89588-V from Santa Cruz Biotechnology
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CROT RNAi - H00054677-R01 from Novus Biologicals
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MISSION® esiRNA - EHU043131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6592 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6592 from Sigma-Aldrich
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CROT siRNA (Human) - CRJ0174 from Cohesion Biosciences
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CROT - MBS827938 from MyBioSource
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shRNA set against Human CROT (NM_021151.3) - SHH269761 from Creative biogene
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CROT shRNA Plasmid (Human) - CHJ0174 from Cohesion Biosciences
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CROT miRNA 3'UTR clone - MiUTR3H-08204 from Creative biogene
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CROT miRNA 3'UTR clone - MiUTR3H-08205 from Creative biogene
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