Gene Symbol | RRN3 |
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Entrez Gene | 54700 |
Alt Symbol | A-270G1.2, TIFIA |
Species | Human |
Gene Type | protein-coding |
Description | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
Other Description | RNA polymerase I-specific transcription initiation factor RRN3|TIF-IA|transcription initiation factor IA|transcription initiation factor TIF-IA |
Swissprots | Q3MHU9 A2RTY9 B4E3T2 B4E0J7 Q9NYV6 Q6IPL4 Q9H4F0 |
Accessions | EAW54754 Q9NYV6 AF227156 AAF66160 AJ272050 CAC07955 AK225662 AK295486 BAG58409 AK300253 BAG62018 AK302994 BAG64131 AK303405 BAG64459 AK304856 BAG65594 AK314769 BAG37307 AK316520 BAH14891 AL110238 BC036182 BC071868 AAH71868 BC104660 AAI04661 BC132688 AAI32689 BC132690 AAI32691 BU676519 CK906270 DA764092 DC376629 HQ258337 ADR83091 XM_005255376 XP_005255433 XM_005255377 XP_005255434 XM_006725198 XP_006725261 XM_006725199 XP_006725262 XM_011522540 XP_011520842 XM_011522541 XP_011520843 XM_011522542 XP_011520844 XM_011546705 XP_011545007 XM_011546706 XP_011545008 NM_001301064 NP_001287993 NM_018427 NP_060897 |
Function | Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:11250903}. |
Rrn3 CRISPR/Cas9 KO Plasmid (h) - sc-403709 from Santa Cruz Biotechnology
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Rrn3 HDR Plasmid (h) - sc-403709-HDR from Santa Cruz Biotechnology
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Rrn3 Double Nickase Plasmid (h) - sc-403709-NIC from Santa Cruz Biotechnology
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Rrn3 Double Nickase Plasmid (h2) - sc-403709-NIC-2 from Santa Cruz Biotechnology
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Rrn3 CRISPR Activation Plasmid (h) - sc-403709-ACT from Santa Cruz Biotechnology
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Rrn3 CRISPR Activation Plasmid (h2) - sc-403709-ACT-2 from Santa Cruz Biotechnology
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Rrn3 Lentiviral Activation Particles (h) - sc-403709-LAC from Santa Cruz Biotechnology
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Rrn3 Lentiviral Activation Particles (h2) - sc-403709-LAC-2 from Santa Cruz Biotechnology
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Rrn3 siRNA (h) - sc-106866 from Santa Cruz Biotechnology
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Rrn3 shRNA Plasmid (h) - sc-106866-SH from Santa Cruz Biotechnology
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Rrn3 shRNA (h) Lentiviral Particles - sc-106866-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU110921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18688 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18688 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10297 from Sigma-Aldrich
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RRN3 siRNA (Human) - CRJ0178 from Cohesion Biosciences
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RRN3 RNAi - H00054700-R01 from Novus Biologicals
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RRN3 - MBS8207827 from MyBioSource
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shRNA set against Human RRN3 (NM_018427.3) - SHH399988 from Creative biogene
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shRNA set against Human RRN3(NM_018427.3) - SHR199122 from Creative biogene
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Human RRN3 siRNA - orb270679 from Biorbyt
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RRN3 shRNA Plasmid (Human) - CHJ0178 from Cohesion Biosciences
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RRN3 miRNA 3'UTR clone - MiUTR1H-09046 from Creative biogene
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