| Gene Symbol |
TLX2
|
| Entrez Gene |
3196
|
| Alt Symbol |
HOX11L1, NCX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
T-cell leukemia homeobox 2
|
| Other Description |
T-cell leukemia homeobox protein 2|homeo box 11-like 1|homeobox protein Hox-11L1|neural crest homeobox protein
|
| Swissprots |
Q9UQ48 O43763 Q9UD56
|
| Accessions |
EAW99630 O43763 AB008501 BAA83463 AB593086 BAJ84026 BC006356 AAH06356 BC006396 BC018611 BU740503 EU446479 ABZ92008 NM_016170 NP_057254
|
| Function |
Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|