Gene Symbol | TLX2 |
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Entrez Gene | 3196 |
Alt Symbol | HOX11L1, NCX |
Species | Human |
Gene Type | protein-coding |
Description | T-cell leukemia homeobox 2 |
Other Description | T-cell leukemia homeobox protein 2|homeo box 11-like 1|homeobox protein Hox-11L1|neural crest homeobox protein |
Swissprots | Q9UQ48 O43763 Q9UD56 |
Accessions | EAW99630 O43763 AB008501 BAA83463 AB593086 BAJ84026 BC006356 AAH06356 BC006396 BC018611 BU740503 EU446479 ABZ92008 NM_016170 NP_057254 |
Function | Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
TLX2 CRISPR/Cas9 KO Plasmid (h) - sc-408687 from Santa Cruz Biotechnology
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TLX2 HDR Plasmid (h) - sc-408687-HDR from Santa Cruz Biotechnology
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TLX2 Double Nickase Plasmid (h) - sc-408687-NIC from Santa Cruz Biotechnology
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TLX2 Double Nickase Plasmid (h2) - sc-408687-NIC-2 from Santa Cruz Biotechnology
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TLX2 CRISPR Activation Plasmid (h) - sc-408687-ACT from Santa Cruz Biotechnology
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TLX2 CRISPR Activation Plasmid (h2) - sc-408687-ACT-2 from Santa Cruz Biotechnology
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TLX2 Lentiviral Activation Particles (h) - sc-408687-LAC from Santa Cruz Biotechnology
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TLX2 Lentiviral Activation Particles (h2) - sc-408687-LAC-2 from Santa Cruz Biotechnology
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TLX2 siRNA (h) - sc-94612 from Santa Cruz Biotechnology
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TLX2 shRNA Plasmid (h) - sc-94612-SH from Santa Cruz Biotechnology
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TLX2 shRNA (h) Lentiviral Particles - sc-94612-V from Santa Cruz Biotechnology
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TLX2 RNAi - H00003196-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21409 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21409 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04331 from Sigma-Aldrich
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TLX2 siRNA (Human) - CRH2184 from Cohesion Biosciences
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TLX2 RNAi - H00003196-R02 from Novus Biologicals
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TLX2 - MBS8223670 from MyBioSource
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shRNA set against Human TLX2 (NM_016170.4) - SHH428072 from Creative biogene
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Human TLX2 siRNA - orb262686 from Biorbyt
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TLX2 shRNA Plasmid (Human) - CHH2184 from Cohesion Biosciences
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