Gene Symbol | TMX1 |
---|---|
Entrez Gene | 81542 |
Alt Symbol | PDIA11, TMX, TXNDC, TXNDC1 |
Species | Human |
Gene Type | protein-coding |
Description | thioredoxin-related transmembrane protein 1 |
Other Description | protein disulfide isomerase family A, member 11|thioredoxin domain containing 1|thioredoxin domain-containing protein 1|transmembrane Trx-related protein |
Swissprots | Q8N487 B2R7A4 Q9H3N1 Q9Y4T6 Q8NBN5 |
Accessions | EAW65678 EAW65679 Q9H3N1 AB048246 BAB20629 AK075395 BAC11593 AK302416 BAH13701 AK303134 BAG64239 AK312905 BAG35751 AL080080 CAB45700 AY358640 AAQ89003 BC016769 BC032834 BC036460 AAH36460 BC050366 BC056874 AAH56874 BU754378 DA203669 DQ891674 ABM82600 DQ894860 ABM85786 NM_030755 NP_110382 |
Function | May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Predominantly found in the endoplasmic reticulum. {ECO:0000269|PubMed:11152479}. |
Tissue Specificity | Ubiquitous. Highly expressed in kidney, liver, placenta and lung. |
TXNDC1 CRISPR/Cas9 KO Plasmid (h) - sc-413426 from Santa Cruz Biotechnology
|
||||||||
TXNDC1 HDR Plasmid (h) - sc-413426-HDR from Santa Cruz Biotechnology
|
||||||||
TXNDC1 Double Nickase Plasmid (h) - sc-413426-NIC from Santa Cruz Biotechnology
|
||||||||
TXNDC1 Double Nickase Plasmid (h2) - sc-413426-NIC-2 from Santa Cruz Biotechnology
|
||||||||
TXNDC1 CRISPR Activation Plasmid (h) - sc-413426-ACT from Santa Cruz Biotechnology
|
||||||||
TXNDC1 CRISPR Activation Plasmid (h2) - sc-413426-ACT-2 from Santa Cruz Biotechnology
|
||||||||
TXNDC1 Lentiviral Activation Particles (h) - sc-413426-LAC from Santa Cruz Biotechnology
|
||||||||
TXNDC1 Lentiviral Activation Particles (h2) - sc-413426-LAC-2 from Santa Cruz Biotechnology
|
||||||||
TXNDC1 siRNA (h) - sc-92249 from Santa Cruz Biotechnology
|
||||||||
TXNDC1 shRNA Plasmid (h) - sc-92249-SH from Santa Cruz Biotechnology
|
||||||||
TXNDC1 shRNA (h) Lentiviral Particles - sc-92249-V from Santa Cruz Biotechnology
|
||||||||
TXNDC RNAi - H00081542-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU038821 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21726 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21726 from Sigma-Aldrich
|
||||||||
TMX1 siRNA (Human) - CRJ2985 from Cohesion Biosciences
|
||||||||
TMX1 - MBS8230879 from MyBioSource
|
||||||||
shRNA set against Human TMX1 (NM_030755.4) - SHH431680 from Creative biogene
|
||||||||
shRNA set against Human TXNDC1(NM_030755.4) - SHL107716 from Creative biogene
|
||||||||
TMX1 shRNA Plasmid (Human) - CHJ2985 from Cohesion Biosciences
|
||||||||
TMX1 miRNA 3'UTR clone - MiUTR1H-10894 from Creative biogene
|