| Gene Symbol |
ERG
|
| Entrez Gene |
2078
|
| Alt Symbol |
erg-3, p55
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
v-ets avian erythroblastosis virus E26 oncogene homolog
|
| Other Description |
TMPRSS2/ERG fusion|ets-related|transcriptional regulator ERG|transcriptional regulator ERG (transforming protein ERG)|v-ets avian erythroblastosis virus E26 oncogene related|v-ets erythroblastosis virus E26 oncogene homolog|v-ets erythroblastosis virus E26 oncogene like
|
| Swissprots |
B4DTW5 Q6XXX4 B4E0T4 P11308 Q16113 Q6XXX5 Q8IXK9
|
| Accessions |
AAA52398 AAB37717 CCV19969 CDI44159 CDL93500 CDL93501 CDM55453 CDM55454 CDM55455 CDM55456 EAX09679 EAX09680 P11308 AA706319 AF015312 AAB65762 AF015313 AAB65763 AK297807 BAG60145 AK300395 BAG62127 AK301277 BAG62837 AK303518 BAG64546 AK304662 BAG65437 AK309469 AM392572 CAL37450 AY204740 AY204741 AAP41719 AY204742 AAP41720 AY204743 BC040168 AAH40168 BE245360 BF431907 DA850637 DC356222 DC394344 DQ204772 DQ204773 DQ831522 EU090248 EU446470 ABZ91999 KP100545 AJT59682 M21535 AAA35811 M21536 R82102 S68130 AAB29724 U17630 XM_011529486 XP_011527788 XM_011529487 XP_011527789 NM_001136154 NP_001129626 NM_001136155 NP_001129627 NM_001243428 NP_001230357 NM_001243429 NP_001230358 NM_001243432 NP_001230361 NM_001291391 NP_001278320 NM_004449 NP_004440 NM_182918 NP_891548 NR_111949 NM_001243433
|
| Function |
Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00237, ECO:0000269|PubMed:17289661}. Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
|
| Top Pathways |
Transcriptional misregulation in cancer
|
