| Gene Symbol |
Pfn4
|
| Entrez Gene |
382562
|
| Alt Symbol |
2900024P18Rik
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
profilin family, member 4
|
| Other Description |
profilin IV|profilin-4
|
| Swissprots |
Q9D6I3
|
| Accessions |
EDL01356 EDL01357 Q9D6I3 AK013595 BAB28919 AY495949 AAS75143 BC094614 BC116888 AAI16889 BC116890 AAI16891 XM_006515138 XP_006515201 XM_006515139 XP_006515202 XM_006515140 XP_006515203 XM_006515141 XP_006515204 NM_028376 NP_082652
|
| Function |
Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin, contrary to other family members (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}.
|
| Tissue Specificity |
Detected in testis (at protein level). {ECO:0000269|PubMed:15591451}.
|
| Top Pathways |
Salmonella infection, Rap1 signaling pathway, Regulation of actin cytoskeleton
|