| Gene Symbol |
WDR35
|
| Entrez Gene |
57539
|
| Alt Symbol |
CED2, IFT121, IFTA1, SRTD7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
WD repeat domain 35
|
| Other Description |
WD repeat-containing protein 35|intraflagellar transport protein 121 homolog|naofen
|
| Swissprots |
Q8NE11 Q9P2L0 Q4ZG01 B3KVI5
|
| Accessions |
AAX88936 EAX00838 EAX00839 EAX00840 EAX00841 Q9P2L0 AB037757 BAA92574 AK022866 AK091205 BAG52306 AK122917 BAG53797 AK315094 AL832903 CAH10636 BC033951 BC036659 AAH36659 BX476609 XM_011533007 XP_011531309 XR_426989 XR_939699 NM_001006657 NP_001006658 NM_020779 NP_065830
|
| Function |
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Required for ciliogenesis. May promote CASP3 activation and TNF-stimulated apoptosis. {ECO:0000269|PubMed:20193664, ECO:0000269|PubMed:21473986}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}.
|
![Western Blot: WDR35 Overexpression Lysate (Adult Normal) [NBP2-06614] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for WDR35.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9774_WDR35%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06614-img0001.jpg)