Gene Symbol | WDR35 |
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Entrez Gene | 57539 |
Alt Symbol | CED2, IFT121, IFTA1, SRTD7 |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat domain 35 |
Other Description | WD repeat-containing protein 35|intraflagellar transport protein 121 homolog|naofen |
Swissprots | Q8NE11 Q9P2L0 Q4ZG01 B3KVI5 |
Accessions | AAX88936 EAX00838 EAX00839 EAX00840 EAX00841 Q9P2L0 AB037757 BAA92574 AK022866 AK091205 BAG52306 AK122917 BAG53797 AK315094 AL832903 CAH10636 BC033951 BC036659 AAH36659 BX476609 XM_011533007 XP_011531309 XR_426989 XR_939699 NM_001006657 NP_001006658 NM_020779 NP_065830 |
Function | Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Required for ciliogenesis. May promote CASP3 activation and TNF-stimulated apoptosis. {ECO:0000269|PubMed:20193664, ECO:0000269|PubMed:21473986}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. |
WDR35 CRISPR/Cas9 KO Plasmid (h) - sc-408266 from Santa Cruz Biotechnology
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WDR35 HDR Plasmid (h) - sc-408266-HDR from Santa Cruz Biotechnology
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WDR35 Double Nickase Plasmid (h) - sc-408266-NIC from Santa Cruz Biotechnology
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WDR35 Double Nickase Plasmid (h2) - sc-408266-NIC-2 from Santa Cruz Biotechnology
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WDR35 CRISPR Activation Plasmid (h) - sc-408266-ACT from Santa Cruz Biotechnology
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WDR35 CRISPR Activation Plasmid (h2) - sc-408266-ACT-2 from Santa Cruz Biotechnology
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WDR35 Lentiviral Activation Particles (h) - sc-408266-LAC from Santa Cruz Biotechnology
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WDR35 Lentiviral Activation Particles (h2) - sc-408266-LAC-2 from Santa Cruz Biotechnology
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WDR35 siRNA (h) - sc-94645 from Santa Cruz Biotechnology
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WDR35 shRNA Plasmid (h) - sc-94645-SH from Santa Cruz Biotechnology
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WDR35 shRNA (h) Lentiviral Particles - sc-94645-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU060441 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22820 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22820 from Sigma-Aldrich
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WDR35 siRNA (Human) - CRJ1520 from Cohesion Biosciences
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WDR35 - MBS8223060 from MyBioSource
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shRNA set against Human WDR35 (NM_020779.3) - SHH446096 from Creative biogene
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shRNA set against Human WDR35(NM_020779.3) - SHL123056 from Creative biogene
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shRNA set against Human WDR35(NM_001006657.1) - SHL123092 from Creative biogene
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Human WDR35 siRNA - orb272021 from Biorbyt
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WDR35 shRNA Plasmid (Human) - CHJ1520 from Cohesion Biosciences
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WDR35 miRNA 3'UTR clone - MiUTR1H-11210 from Creative biogene
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WDR35 miRNA 3'UTR clone - MiUTR1H-11211 from Creative biogene
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