CTNNA2

Gene Symbol CTNNA2
Entrez Gene 1496
Alt Symbol CAP-R, CAPR, CT114, CTNR
Species Human
Gene Type protein-coding
Description catenin (cadherin-associated protein), alpha 2
Other Description alpha N-catenin|alpha-N-catenin|alpha-catenin-related protein|cadherin-associated protein, related|cancer/testis antigen 114|catenin alpha-2
Swissprots B7Z2W7 Q53TM8 B3KXE5 Q53R26 Q53R33 Q4ZFW1 Q7Z3L1 B7Z898 Q7Z3Y0 B7Z352 Q53T67 P26232 Q53T71
Accessions AAX88946 AAX93241 AAY14758 AAY14763 AAY15008 AAY15073 EAW99563 EAW99564 EAW99565 P26232 AK127226 BAG54457 AK294362 BAH11745 AK295181 BAH12003 AK295493 BAH12088 AK303035 BAH13884 AL708938 BC040458 AAH40458 BC052996 AAH52996 BI599815 BX537769 CAD97832 BX648368 DA313393 DC341423 HQ589336 AEF32484 M94151 AAA58407 XM_006711949 XP_006712012 XM_011532555 XP_011530857 XM_011532556 XP_011530858 XM_011532557 XP_011530859 NM_001164883 NP_001158355 NM_001282597 NP_001269526 NM_001282598 NP_001269527 NM_001282599 NP_001269528 NM_001282600 NP_001269529 NM_004389 NP_004380
Function May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system. Regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Functions in the control of startle modulation (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16182284}. Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, adherens junction {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell projection, axon {ECO:0000250}. Note=Recruited to the nucleus upon ZNF639 overexpression.
Top Pathways Adherens junction, Tight junction, Leukocyte transendothelial migration, Endometrial cancer, Arrhythmogenic right ventricular cardiomyopathy (ARVC)

α N-catenin CRISPR/Cas9 KO Plasmid (h) - sc-405168 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin HDR Plasmid (h) - sc-405168-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin Double Nickase Plasmid (h) - sc-405168-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin Double Nickase Plasmid (h2) - sc-405168-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin CRISPR Activation Plasmid (h) - sc-405168-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin CRISPR Activation Plasmid (h2) - sc-405168-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin Lentiviral Activation Particles (h) - sc-405168-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin Lentiviral Activation Particles (h2) - sc-405168-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α N-catenin siRNA (h) - sc-43019 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α N-catenin shRNA Plasmid (h) - sc-43019-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α N-catenin shRNA (h) Lentiviral Particles - sc-43019-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU059331 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6734 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07500 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07500

CTNNA2 siRNA (Human) - CRH1058 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CTNNA2 - MBS8221492 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CTNNA2 (NM_004389.3) - SHH271273 from Creative biogene

Category siRNA
Species Reactivities Human

CTNNA2 shRNA Plasmid (Human) - CHH1058 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CTNNA2 miRNA 3'UTR clone - MiUTR3H-00301 from Creative biogene

Species Reactivities Human

CTNNA2 miRNA 3'UTR clone - MiUTR3H-00302 from Creative biogene

Species Reactivities Human
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