| Gene Symbol |
WDR36
|
| Entrez Gene |
134430
|
| Alt Symbol |
GLC1G, TA-WDRP, TAWDRP, UTP21
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
WD repeat domain 36
|
| Other Description |
T-cell activation WD repeat protein|T-cell activation WD repeat-containing protein|WD repeat-containing protein 36
|
| Swissprots |
A2RUS4 Q68E02 Q8NI36 Q8N1Q2
|
| Accessions |
EAW49035 EAW49036 Q8NI36 AF385437 AAM43838 AK055664 AK074202 AK095312 BAC04527 AL832494 BC037427 BC133025 AAI33026 BC136517 AAI36518 CR749211 CAH18068 XM_011543163 XP_011541465 NM_139281 NP_644810
|
| Function |
Involved in the nucleolar processing of SSU 18S rRNA. Involved in T-cell activation and highly coregulated with IL2. {ECO:0000269|PubMed:21051332}.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:21051332, ECO:0000269|PubMed:22002106}.
|
| Tissue Specificity |
Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues, strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve. {ECO:0000269|PubMed:15677485}.
|
| Top Pathways |
Ribosome biogenesis in eukaryotes
|
![Western Blot: WDR36 Overexpression Lysate (Adult Normal) [NBP2-05576] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for WDR36.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/17720_WDR36%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-05576-img0001.jpg)