Gene Symbol | WDR36 |
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Entrez Gene | 134430 |
Alt Symbol | GLC1G, TA-WDRP, TAWDRP, UTP21 |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat domain 36 |
Other Description | T-cell activation WD repeat protein|T-cell activation WD repeat-containing protein|WD repeat-containing protein 36 |
Swissprots | A2RUS4 Q68E02 Q8NI36 Q8N1Q2 |
Accessions | EAW49035 EAW49036 Q8NI36 AF385437 AAM43838 AK055664 AK074202 AK095312 BAC04527 AL832494 BC037427 BC133025 AAI33026 BC136517 AAI36518 CR749211 CAH18068 XM_011543163 XP_011541465 NM_139281 NP_644810 |
Function | Involved in the nucleolar processing of SSU 18S rRNA. Involved in T-cell activation and highly coregulated with IL2. {ECO:0000269|PubMed:21051332}. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:21051332, ECO:0000269|PubMed:22002106}. |
Tissue Specificity | Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. In ocular tissues, strong expression in iris, sclera, ciliary muscle, ciliary body, retina and optic nerve. {ECO:0000269|PubMed:15677485}. |
Top Pathways | Ribosome biogenesis in eukaryotes |
WDR36 CRISPR/Cas9 KO Plasmid (h) - sc-410298 from Santa Cruz Biotechnology
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WDR36 HDR Plasmid (h) - sc-410298-HDR from Santa Cruz Biotechnology
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WDR36 Double Nickase Plasmid (h) - sc-410298-NIC from Santa Cruz Biotechnology
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WDR36 Double Nickase Plasmid (h2) - sc-410298-NIC-2 from Santa Cruz Biotechnology
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WDR36 CRISPR Activation Plasmid (h) - sc-410298-ACT from Santa Cruz Biotechnology
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WDR36 CRISPR Activation Plasmid (h2) - sc-410298-ACT-2 from Santa Cruz Biotechnology
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WDR36 Lentiviral Activation Particles (h) - sc-410298-LAC from Santa Cruz Biotechnology
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WDR36 Lentiviral Activation Particles (h2) - sc-410298-LAC-2 from Santa Cruz Biotechnology
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WDR36 siRNA (h) - sc-91824 from Santa Cruz Biotechnology
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WDR36 shRNA Plasmid (h) - sc-91824-SH from Santa Cruz Biotechnology
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WDR36 shRNA (h) Lentiviral Particles - sc-91824-V from Santa Cruz Biotechnology
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WDR36 RNAi - H00134430-R01 from Novus Biologicals
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MISSION® esiRNA - EHU008401 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22821 from Sigma-Aldrich
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WDR36 siRNA (Human) - CRJ5144 from Cohesion Biosciences
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WDR36 - MBS8211662 from MyBioSource
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shRNA set against Human Wdr36 (NM_139281.2) - SHH446112 from Creative biogene
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shRNA set against Human WDR36(NM_139281.2) - SHL122774 from Creative biogene
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WDR36 shRNA Plasmid (Human) - CHJ5144 from Cohesion Biosciences
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WDR36 miRNA 3'UTR clone - MiUTR1H-11212 from Creative biogene
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