Gene Symbol |
SPSB1
|
Entrez Gene |
80176
|
Alt Symbol |
SSB-1, SSB1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
splA/ryanodine receptor domain and SOCS box containing 1
|
Other Description |
SPRY domain-containing SOCS box protein 1|SPRY domain-containing SOCS box protein SSB-1|novel SPRY domain containing protein
|
Swissprots |
A2A275 Q96BD6 Q9BRY9 Q5TIH9 Q9H6C5 Q59FA1
|
Accessions |
EAW71617 EAW71618 Q96BD6 AB209559 BAD92796 AF131840 AF403026 AAL57345 AK026046 BAB15335 AK130055 BAC85287 AK225417 BC005852 AAH05852 BC015711 AAH15711 DB242202 HQ447409 ADQ31895 NM_025106 NP_079382
|
Function |
Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269|PubMed:15601820}.
|
Subcellular Location |
Cytoplasm {ECO:0000305}.
|