Gene Symbol | SPSB1 |
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Entrez Gene | 80176 |
Alt Symbol | SSB-1, SSB1 |
Species | Human |
Gene Type | protein-coding |
Description | splA/ryanodine receptor domain and SOCS box containing 1 |
Other Description | SPRY domain-containing SOCS box protein 1|SPRY domain-containing SOCS box protein SSB-1|novel SPRY domain containing protein |
Swissprots | A2A275 Q96BD6 Q9BRY9 Q5TIH9 Q9H6C5 Q59FA1 |
Accessions | EAW71617 EAW71618 Q96BD6 AB209559 BAD92796 AF131840 AF403026 AAL57345 AK026046 BAB15335 AK130055 BAC85287 AK225417 BC005852 AAH05852 BC015711 AAH15711 DB242202 HQ447409 ADQ31895 NM_025106 NP_079382 |
Function | Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. {ECO:0000269|PubMed:15601820}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
SSB-1 CRISPR/Cas9 KO Plasmid (h) - sc-408087 from Santa Cruz Biotechnology
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SSB-1 HDR Plasmid (h) - sc-408087-HDR from Santa Cruz Biotechnology
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SSB-1 Double Nickase Plasmid (h) - sc-408087-NIC from Santa Cruz Biotechnology
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SSB-1 Double Nickase Plasmid (h2) - sc-408087-NIC-2 from Santa Cruz Biotechnology
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SSB-1 CRISPR Activation Plasmid (h) - sc-408087-ACT from Santa Cruz Biotechnology
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SSB-1 CRISPR Activation Plasmid (h2) - sc-408087-ACT-2 from Santa Cruz Biotechnology
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SSB-1 Lentiviral Activation Particles (h) - sc-408087-LAC from Santa Cruz Biotechnology
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SSB-1 Lentiviral Activation Particles (h2) - sc-408087-LAC-2 from Santa Cruz Biotechnology
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SSB-1 siRNA (h) - sc-88214 from Santa Cruz Biotechnology
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SSB-1 shRNA Plasmid (h) - sc-88214-SH from Santa Cruz Biotechnology
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SSB-1 shRNA (h) Lentiviral Particles - sc-88214-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU134891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20536 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20536 from Sigma-Aldrich
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SPSB1 siRNA (Human) - CRJ2785 from Cohesion Biosciences
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SPSB1 - MBS8217054 from MyBioSource
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shRNA set against Human SPSB1 (NM_025106.3) - SHH417424 from Creative biogene
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SPSB1 shRNA Plasmid (Human) - CHJ2785 from Cohesion Biosciences
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SPSB1 miRNA 3'UTR clone - MiUTR3H-12033 from Creative biogene
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