| Gene Symbol |
PIGX
|
| Entrez Gene |
54965
|
| Alt Symbol |
PIG-X
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosphatidylinositol glycan anchor biosynthesis, class X
|
| Other Description |
GPI-mannosyltransferase subunit|phosphatidylinositol-glycan biosynthesis class X protein
|
| Swissprots |
Q9NWZ2 Q8TBF5
|
| Accessions |
EAW53637 EAW53638 EAW53640 Q8TBF5 AA879458 AK000529 BAA91233 AK294340 BAG57610 BC022542 AAH22542 BG715890 BQ130655 BU740645 CN404010 HQ447204 ADQ31691 NM_001166304 NP_001159776 NM_017861 NP_060331
|
| Function |
Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Top Pathways |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|
