SEPSECS

Gene Symbol SEPSECS
Entrez Gene 51091
Alt Symbol LP, PCH2D, SLA, SLA/LP
Species Human
Gene Type protein-coding
Description Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Other Description O-phosphoseryl-tRNA(Sec) selenium transferase|SLA-p35|SLA/LP autoantigen|UGA suppressor tRNA-associated protein|liver-pancreas antigen|soluble liver antigen|soluble liver antigen/liver pancreas antigen|tRNA(Ser/Sec)-associated antigenic protein
Swissprots Q9HD40 Q9Y353 Q17RT1 Q0D2P3 A8K8W1 Q9NXZ5 Q9UGM9
Accessions EAW92831 EAW92832 EAW92833 EAW92834 EAW92835 Q9HD40 AF146396 AAD33963 AF282065 AAG00491 AJ238617 CAB62209 AJ277541 CAB89517 AK292476 BAF85165 AL133065 AW515989 BC012188 BC023539 AAH23539 BC117202 AAI17203 BC126213 AAI26214 BX648976 CN429794 DA155173 EU832146 ACE87496 EU832239 ACE86809 XM_005248168 XP_005248225 XM_006713965 XP_006714028 XM_011513846 XP_011512148 XM_011513847 XP_011512149 XM_011513848 XP_011512150 NM_016955 NP_058651 NM_001159728
Function Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. {ECO:0000269|PubMed:17142313}.
Subcellular Location Cytoplasm.
Tissue Specificity Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells.
Top Pathways Selenocompound metabolism, Aminoacyl-tRNA biosynthesis

SLA/LP (E-12) - sc-131782 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SLA/LP (E-12): sc-131782. Western blot analysis of SLA/LP expression in non-transfected 293T: sc-117752 (A), human SLA/LP transfected 293T: sc-177926 (B) and Jurkat (C) whole cell lysates.

SLA/LP (H-300) - sc-366238 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

SLA/LP (W-23) - sc-102105 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
SLA/LP (W-23): sc-102105. Western blot analysis of SLA/LP expression in Jurkat whole cell lysate.

Anti-Soluble Liver/Pancreas Antigen antibody - ab197101 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed paraffin embedded human fetal stomach labeling Soluble Liver/Pancreas Antigen using ab197101 at 1/500 dilution

Anti-Soluble Liver/Pancreas Antigen antibody - ab154287 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Soluble Liver/Pancreas Antigen antibody (ab154287) at 1/5000 dilution + A431 whole cell lysate at 30 µg

Anti-Soluble Liver/Pancreas Antigen antibody - C-terminal - ab174136 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Soluble Liver/Pancreas Antigen antibody - C-terminal (ab174136) at 1/100 dilution + HepG2 cell line lysates at 35 µg

Anti-Soluble Liver/Pancreas Antigen antibody - ab56033 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Soluble Liver/Pancreas Antigen antibody (ab56033) at 1 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SEPSECS Antibody (aa444-474, AP) - LS-C240569 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPSECS Antibody (aa444-474, Biotin) - LS-C240571 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPSECS Antibody (aa444-474, PE) - LS-C240574 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPSECS Antibody (aa444-474, FITC) - LS-C240572 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPSECS Antibody (aa443-474) - LS-C325002 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPSECS Antibody (aa444-474, Azide-free, HRP) - LS-C248113 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPSECS Antibody (aa444-474, APC) - LS-C240570 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SEPSECS Antibody - LS-C334982 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of HeLa cell using SEPSECS antibody. Blue: DAPI for nuclear staining.

Anti-SEPSECS Antibody (aa61-110) - LS-C30488 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SEPSECS antibody LS-C30488 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-SEPSECS Antibody (aa444-474) - LS-C158939 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SEPSECS Antibody western blot of HepG2 cell line lysates (35 ug/lane). The SEPSECS Antibody detected the SEPSECS protein (arrow).

Slap Antibody - NBP1-80744 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Slap Antibody [NBP1-80744] - Staining of human lung shows strong cytoplasmic positivity in macrophages.

Soluble Liver/Pancreas Antigen Antibody - NBP2-20454 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Soluble Liver/Pancreas Antigen Antibody [NBP2-20454] - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE gel, diluted at 1:5000.

Anti-SLA/LP antibody produced in rabbit - AV41159 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLA/LP: <B>Cat. No. AV41159</B>: Immunohistochemistry of SLA/LP in Human Kidney tissue with SLA/LP antibody at 4-8 μg/mL.

Anti-SEPSECS antibody produced in rabbit - SAB2700720 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SEPSECS: <B>Cat. No. SAB2700720</B>: Western Blot analysis of SEPSECS in extracts from <B>Lanes</B><BR/>A. A431 using <B>Cat. No. SAB2700720</B> at a 1:5000 dilution.

SLA antibody - N-terminal region (ARP41159_P050) - ARP41159_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SEPSECS-Antibody-C-term - AP18403b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SEPSECS Antibody (C-term) (Cat. #AP18403b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SEPSECS Antibody detected the SEPSECS protein (arrow).

SEPSECS Antibody - C-terminal region (OAAB13937) - OAAB13937 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

SEPSECS Antibody (OACA01979) - OACA01979 from Aviva Systems Biology

Prices $270.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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