| Gene Symbol |
SEPSECS
|
| Entrez Gene |
51091
|
| Alt Symbol |
LP, PCH2D, SLA, SLA/LP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
|
| Other Description |
O-phosphoseryl-tRNA(Sec) selenium transferase|SLA-p35|SLA/LP autoantigen|UGA suppressor tRNA-associated protein|liver-pancreas antigen|soluble liver antigen|soluble liver antigen/liver pancreas antigen|tRNA(Ser/Sec)-associated antigenic protein
|
| Swissprots |
Q9HD40 Q9Y353 Q17RT1 Q0D2P3 A8K8W1 Q9NXZ5 Q9UGM9
|
| Accessions |
EAW92831 EAW92832 EAW92833 EAW92834 EAW92835 Q9HD40 AF146396 AAD33963 AF282065 AAG00491 AJ238617 CAB62209 AJ277541 CAB89517 AK292476 BAF85165 AL133065 AW515989 BC012188 BC023539 AAH23539 BC117202 AAI17203 BC126213 AAI26214 BX648976 CN429794 DA155173 EU832146 ACE87496 EU832239 ACE86809 XM_005248168 XP_005248225 XM_006713965 XP_006714028 XM_011513846 XP_011512148 XM_011513847 XP_011512149 XM_011513848 XP_011512150 NM_016955 NP_058651 NM_001159728
|
| Function |
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. {ECO:0000269|PubMed:17142313}.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
Primarily expressed in liver, pancreas, kidney and lung. Overexpressed in PHA-stimulated T-cells.
|
| Top Pathways |
Selenocompound metabolism, Aminoacyl-tRNA biosynthesis
|
![Western Blot: Soluble Liver/Pancreas Antigen Overexpression Lysate (Adult Normal) [NBL1-15816] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Soluble Liver/Pancreas Antigen.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9507_Soluble%2520Liver-Pancreas%2520Antigen%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15816-img0002.jpg)