PMCH
| Gene Symbol | PMCH |
|---|---|
| Entrez Gene | 5367 |
| Alt Symbol | MCH |
| Species | Human |
| Gene Type | protein-coding |
| Description | pro-melanin-concentrating hormone |
| Other Description | pro-MCH |
| Swissprots | Q16044 Q8WVG0 P20382 |
| Accessions | AAB27493 EAW97693 P20382 AV723033 BC018048 AAH18048 CB047053 DQ892335 ABM83261 DQ895540 ABM86466 M57703 AAA63214 NM_002674 NP_002665 |
| Function | MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Predominantly expressed in lateral hypothalamus, also detected in pallidum, neocortex and cerebellum. Also found in thymus, brown adipose tissue, duodenum and testis (spermatogonia, early spermatocytes and Sertoli cells). No expression in peripheral blood. In brain exclusively mature MCH and NEI peptides are present. In peripheral tissues a large product, encompassing the NEI and MCH domains of the precursor, is found predominantly. {ECO:0000269|PubMed:9191099}. |
PMCH-Over-expression-Lysate - LY10707a from Abgent, a WuXi AppTec company
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PMCH overexpression lysate - LY419178 from Acris Antibodies
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PMCH Overexpression Lysate (Native) - NBP2-08082 from Novus Biologicals
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Panoply™ Human PMCH Knockdown Stable Cell Line - CSC-DC011998 from Creative biogene
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