| Gene Symbol |
TCAF1
|
| Entrez Gene |
9747
|
| Alt Symbol |
FAM115A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TRPM8 channel-associated factor 1
|
| Other Description |
TRP channel-associated factor 1|family with sequence similarity 115, member A|protein FAM115A
|
| Swissprots |
Q9Y4C2 Q9BW63 Q7L665 Q75KM8 A8K6E0 Q75KM9
|
| Accessions |
AAQ96852 AAQ96853 EAW55623 Q9Y4C2 AB018281 BAA34458 AF086218 AF119896 AAF69650 AK001640 AK291605 BAF84294 AK294312 BAH11732 AK299911 BAG61749 BC000609 AAH00609 BC039457 BU947884 DA196926 DA317873 DQ786274 XM_005250074 XP_005250131 XM_005250075 XP_005250132 XM_005250076 XP_005250133 XM_005250077 XP_005250134 XM_006716191 XP_006716254 XM_006716192 XP_006716255 NM_001206938 NP_001193867 NM_001206941 NP_001193870 NM_014719 NP_055534
|
| Function |
Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner. {ECO:0000269|PubMed:25559186}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:25559186}. Note=Colocalizes with TRPM8 on the plasma membrane. {ECO:0000269|PubMed:25559186}.
|
| Tissue Specificity |
Isoform 2 is expressed in the prostate and strongly expressed in cancerous prostate samples. {ECO:0000269|PubMed:25559186}.
|