| Gene Symbol |
Hmgcs1
|
| Entrez Gene |
29637
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
| Other Description |
3-hydroxy-3-methylglutaryl coenzyme A synthase|3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)|HMG-CoA synthase|hydroxymethylglutaryl-CoA synthase 1|hydroxymethylglutaryl-CoA synthase, cytoplasmic
|
| Swissprots |
P17425
|
| Accessions |
EDM10425 EDM10426 P17425 AY724522 FQ210571 FQ211444 X52625 CAA36852 XM_006231959 XP_006232021 NM_017268 NP_058964
|
| Function |
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Terpenoid backbone biosynthesis, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism
|