| Gene Symbol | Hmgcs1 |
|---|---|
| Entrez Gene | 29637 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| Other Description | 3-hydroxy-3-methylglutaryl coenzyme A synthase|3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble)|HMG-CoA synthase|hydroxymethylglutaryl-CoA synthase 1|hydroxymethylglutaryl-CoA synthase, cytoplasmic |
| Swissprots | P17425 |
| Accessions | EDM10425 EDM10426 P17425 AY724522 FQ210571 FQ211444 X52625 CAA36852 XM_006231959 XP_006232021 NM_017268 NP_058964 |
| Function | This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Terpenoid backbone biosynthesis, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism |
CompoZr® Knockout ZFN Kit - CKOZFN55091 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND55091 from Sigma-Aldrich
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HMGCS1 siRNA (Rat) - CRR1288 from Cohesion Biosciences
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HMGCS1 - MBS8201715 from MyBioSource
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shRNA set against Rat HMGCS1 (NM_017268.1) - SHH313393 from Creative biogene
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shRNA set against Rat Hmgcs1(NM_017268.1) - SHH125435 from Creative biogene
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Rat HMGCS1 siRNA - orb296137 from Biorbyt
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HMGCS1 shRNA Plasmid (Rat) - CHR1288 from Cohesion Biosciences
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HMGCS1 miRNA 3'UTR clone - MiUTR1R-02452 from Creative biogene
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