| Gene Symbol |
TACR3
|
| Entrez Gene |
6870
|
| Alt Symbol |
HH11, NK-3R, NK3R, NKR, TAC3RL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tachykinin receptor 3
|
| Other Description |
NK-3 receptor|neurokinin B receptor|neurokinin beta receptor|neuromedin-K receptor
|
| Swissprots |
P29371 Q0P510
|
| Accessions |
AAB21706 CAA46291 EAX06173 P29371 AY462099 AAR23926 BC095527 AAH95527 BC121806 AAI21807 BC122551 AAI22552 M89473 AAA36366 NM_001059 NP_001050
|
| Function |
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|
![Western Blot: Neurokinin B Receptor Overexpression Lysate (Adult Normal) [NBP2-08339] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Neurokinin B Receptor.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5204_Neurokinin%2520B%2520Receptor%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08339-img0001.jpg)
![Western Blot: Neurokinin B Receptor Overexpression Lysate (Adult Normal) [NBP2-10908] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Neurokinin B Receptor.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7368_Neurokinin%2520B%2520Receptor%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10908-img0001.jpg)