| Gene Symbol |
TACR3
|
| Entrez Gene |
6870
|
| Alt Symbol |
HH11, NK-3R, NK3R, NKR, TAC3RL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tachykinin receptor 3
|
| Other Description |
NK-3 receptor|neurokinin B receptor|neurokinin beta receptor|neuromedin-K receptor
|
| Swissprots |
P29371 Q0P510
|
| Accessions |
AAB21706 CAA46291 EAX06173 P29371 AY462099 AAR23926 BC095527 AAH95527 BC121806 AAI21807 BC122551 AAI22552 M89473 AAA36366 NM_001059 NP_001050
|
| Function |
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|