CUX1

Gene Symbol CUX1
Entrez Gene 1523
Alt Symbol CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75
Species Human
Gene Type protein-coding
Description cut-like homeobox 1
Other Description CCAAT displacement protein|cut homolog|golgi integral membrane protein 6|homeobox protein cux-1|protein CASP|putative protein product of Nbla10317
Swissprots Q86UJ7 J3KPQ6 G3V1Z6 Q75MT2 B3KV79 Q9UEV5 B3KWH3 J3KQV9 P39880 B4DZZ2 Q75LE5 Q53GU9 Q8TBS3 Q13948 Q6NYH4 B3KWH8 Q75MT3
Accessions AAC78778 AAP22331 AAS07388 AAS07406 AAS07410 AAS07523 EAW50227 EAW50228 P39880 Q13948 AB075522 BAE45765 AK056307 AK122726 BAG53691 AK125097 BAG54140 AK222832 BAD96552 AK297548 BAG59942 AK303151 BAG64254 BC007204 BC012323 BC025422 AAH25422 BC040199 BC045562 BC066592 AAH66592 DC410774 L12579 AAA35654 M74099 XM_005250150 XP_005250207 XM_005250151 XP_005250208 XM_005250154 XP_005250211 XM_006715854 XP_006715917 XM_006715855 XP_006715918 XM_006715856 XP_006715919 XM_011515823 XP_011514125 XM_011515824 XP_011514126 XM_011515825 XP_011514127 NM_001202543 NP_001189472 NM_001202544 NP_001189473 NM_001202545 NP_001189474 NM_001202546 NP_001189475 NM_001913 NP_001904 NM_181500 NP_852477 NM_181552 NP_853530
Function Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity). {ECO:0000250}.
Subcellular Location Nucleus.

CDP (B-10) - sc-514008 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CDP (B-10): sc-514008. Western blot analysis of CDP expression in BJAB (A) and K-562 (B) nuclear extracts.

CDP (C-20) - sc-6327 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CDP (C-20): sc-6327. Western blot analysis of CDP expression in HeLa (A) and NIH/3T3 (B) nuclear extracts.

CDP (M-222) - sc-13024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CDP (M-222): sc-13024. Western blot analysis of CDP expression in K-562 (A) and BJAB (B) nuclear extracts.

CDP (N-19) - sc-6328 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CDP (SS9) - sc-101003 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
CDP (SS9): sc-101003. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human malignant lymphoma, diffuse large B-cell tissue showing cytoplasmic localization.

Anti-CUTL1 antibody - ab167553 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CUTL1 antibody (ab167553) at 1 µg/mlLane 1 : CUTL1 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.

Anti-CUTL1 antibody - ab85994 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CUTL1 antibody (ab85994) at 1/1000 dilutionLane 1 : Uninduced (negative control) culture of E.coli Lane 2 : Induced culture of E.coli Secondaryanti-Rabbit IgG HRP conjugated at 1/1000 dilution

Anti-CUTL1 antibody - ab73885 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CUTL1 antibody (ab73885) at 1/500 dilutionLane 1 : extracts from K562 cellsLane 2 : extracts from K562 cells with immunizing peptide at 10 µgLysates/proteins at 20 µg per lane.

Anti-CUTL1 antibody - ab98273 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CUTL1 antibody (ab98273) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

Anti-CUTL1 antibody [2A10] - ab54583 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A10
Immunohistochemistry analysis of ab54583 antibody at 5 ug/ml with formalin-fixed, paraffin-embedded Human Spleen

Anti-CUTL1 antibody - C-terminal - ab138740 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CUTL1 antibody - C-terminal (ab138740) at 1/100 dilution + MDA-MB453 cell lysate at 35 µg

Anti-CUX1 / CASP Antibody (aa143-192) - LS-C107935 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CUX1 / CUTL1 antibody LS-C107935 Western blot of Fetal Spleen lysate.

Anti-CUX1 / CASP Antibody (aa10-59) - LS-C118883 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from K562 cells, using CUTL1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CUX1 / CASP Antibody (aa1354-1382, APC) - LS-C255724 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa1354-1382, AP) - LS-C255723 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa1354-1382, Biotin) - LS-C255725 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa1354-1382, FITC) - LS-C255726 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa1354-1382, Azide-free, HRP) - LS-C255727 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa1354-1382, PE) - LS-C255728 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa639-666, AP) - LS-C255730 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (Gln24) - LS-C177120 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of CDP (Q24) pAb in extracts from K562 cells.

Anti-CUX1 / CASP Antibody (aa639-666, APC) - LS-C255729 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa639-666) - LS-C159420 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CUX1 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The CUX1 antibody detected the CUX1 protein (arrow).

Anti-CUX1 / CASP Antibody (aa639-666, Biotin) - LS-C255731 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CUX1 / CASP Antibody (aa639-666, FITC) - LS-C255732 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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