IWS1

Gene Symbol IWS1
Entrez Gene 55677
Alt Symbol -
Species Human
Gene Type protein-coding
Description IWS1 homolog (S. cerevisiae)
Other Description IWS1-like protein|interacts with Spt6|protein IWS1 homolog
Swissprots Q9NV97 Q96MI7 Q6P157 Q8N3E8 Q96ST2 Q9NWH8 Q2TB65
Accessions EAW95321 Q96ST2 AI638093 AK000868 BAA91402 AK001717 BAA91858 AK027561 BAB55198 AK056881 BAB71301 AK294669 BAG57836 AK295970 BAG58746 AK296848 BAG59414 AK309006 AL834178 CAD38875 BC017012 AAH17012 BC022051 BC022892 BC065279 AAH65279 BC110536 AAI10537 BC110537 AAI10538 DA268882 XM_005263707 XP_005263764 XM_006712626 XP_006712689 XM_011511450 XP_011509752 XM_011511451 XP_011509753 XM_011511452 XP_011509754 XR_427099 XR_922960 NM_017969 NP_060439
Function Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription. {ECO:0000269|PubMed:17184735, ECO:0000269|PubMed:17234882, ECO:0000269|PubMed:19141475}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00649, ECO:0000269|PubMed:17184735, ECO:0000269|PubMed:17234882}.

IWS1 Antibody - 5681 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using IWS1 Antibody.

hIws1 (D-14) - sc-168086 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
hIws1 (D-14): sc-168086. Western blot analysis of hIws1 expression in ARPE-19 (A) and NIH/3T3 (B) whole cell lysates.

Anti-IWS1 antibody - ab103243 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IWS1 antibody (ab103243) at 1/100 dilution + Y-79 cell line lysates at 35 µg

Anti-IWS1 antibody - ab118209 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IWS1 antibody (ab118209) at 1/500 dilution + Human fetal muscle lysate

Anti-IWS1 antibody - N-terminal - ab195309 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: ab195309 used for IP at 6 µg per reaction. For blotting immunoprecipitated IWS1, ab195309 was used at 0.4 µg/mL.

Anti-IWS1 Antibody (N-Terminus) - LS-C143813 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IWS1 Antibody (aa71-120) - LS-C151948 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IWS1 antibody Western Blot of Human Kidney.

Anti-IWS1 Antibody (aa591-743) - LS-C178658 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IWS1 Antibody - NBP1-94064 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: IWS1 Antibody [NBP1-94064] - Staining of human tonsil shows strong nuclear positivity in reaction center cells.

Anti-IWS1 antibody produced in rabbit - HPA035719 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IWS1: <B>Cat. No. HPA035719</B>: Immunohistochemical staining of human tonsil shows strong nuclear positivity in reaction center cells.

IWS1 antibody - N-terminal region (ARP65333_P050) - ARP65333_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

IWS1 antibody - orb78074 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin embedded fetal liver showing cytoplasmic staining using IWS1 antibody

IWS1 antibody - 70R-18041 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti -IWS1 - 211570 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

IWS1 Polyclonal Antibody - A4839 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

IWS1 Polyclonal Antibody - A7375 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using IWS1 antibody.

IWS1 Antibody - abx003668 from Abbexa

Host Rabbit
Clonality Polyclonal

IWS1 Antibody - abx037162 from Abbexa

Host Rabbit
Clonality Polyclonal

IWS1 / IWS1L antibody - 16943-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Human brain tissue were subjected to SDS PAGE followed by western blot with 16943-1-AP(IWS1 antibody) at dilution of 1:500

Anti-IWS1, Polyclonal Antibody - 25-A4839 from ARP American Research Products

Prices $419.00, $619.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

Anti-IWS1 antibody - STJ29512 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

IWS1 antibody - STJ26905 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

IWS1 antibody - 16943-1-AP from Proteintech Group

Prices $279.00
Sizes con: 37 μg/150μl
Host Rabbit
Clonality Polyclonal
HeLa cells were subjected to SDS PAGE followed by western blot with 16943-1-AP( IWS1 Antibody) at dilution of 1:3000

IWS1, Polyclonal Antibody - MBS852224 from MyBioSource

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

IWS1, Polyclonal Antibody - MBS2527292 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Search more