BACH2

Gene Symbol BACH2
Entrez Gene 60468
Alt Symbol BTBD25
Species Human
Gene Type protein-coding
Description BTB and CNC homology 1, basic leucine zipper transcription factor 2
Other Description BTB and CNC homolog 2|transcription regulator protein BACH2
Swissprots Q5T793 E1P518 Q9NTS5 Q59H70 Q9BYV9
Accessions CBX47436 EAW48530 EAW48531 EAW48532 EAW48533 EAW48534 Q9BYV9 AA885077 AB208889 BAD92126 AF357835 AAK48898 AI524722 AJ271878 CAC28130 AK309526 AL512739 BC070239 BC166613 AAI66613 CN261405 DB077323 DB240991 HE578163 CCD17752 HE578164 CCD17753 HE578165 CCD17754 HE578166 CCD17755 HE578167 CCD17756 HE578168 CCD17757 HE578169 CCD17758 HE578170 CCD17759 HE578171 CCD17760 HE578172 CCD17761 HE578173 CCD17762 HE578174 CCD17763 HE578175 CCD17764 HE578176 CCD17765 XM_005248758 XP_005248815 XM_005248759 XP_005248816 XM_011536037 XP_011534339 XM_011536038 XP_011534340 XM_011536039 XP_011534341 XM_011536040 XP_011534342 XM_011536041 XP_011534343 XM_011536042 XP_011534344 XM_011536043 XP_011534345 NM_001170794 NP_001164265 NM_021813 NP_068585
Function Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. {ECO:0000250, ECO:0000269|PubMed:17018862}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17018862}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:17018862}. Note=Nucleocytoplasmic shuttling is controlled by phosphorylation.
Tissue Specificity B-cell specific.

BACH2 Antibody - 12809 from Cell Signaling Technology

Prices $239.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from RL-7 and Daudi cells using BACH2 Antibody.

BACH2 (E-16) - sc-14702 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BACH2 (L-17) - sc-14704 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BACH2 (L-17): sc-14704. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lymph node tissue showing nuclear and cytoplasmic staining of cells in germinal centers and cells in non-germinal centers.

Anti-BACH2 antibody - ab83364 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BACH2 antibody (ab83364) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BACH2 Antibody (Internal) - LS-C153572 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa822-849, AP) - LS-C212903 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (Internal) IHC-plus™ - LS-B7533 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BACH2 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7533 concentration 10 ug/ml.

Anti-BACH2 Antibody (C-Terminus) - LS-C109760 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BACH2 antibody LS-C109760 Western blot of Fetal Thymus lysate.

Anti-BACH2 Antibody (aa822-849, Biotin) - LS-C212905 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa815-841, FITC) - LS-C212906 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa815-841, Azide-free, HRP) - LS-C212907 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa822-849, PE) - LS-C212908 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa282-312, AP) - LS-C212909 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa282-312, APC) - LS-C212910 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa282-312, Biotin) - LS-C212911 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa283-312) - LS-C156727 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BACH2 Antibody western blot of K562 cell line lysates (35 ug/lane). The BACH2 antibody detected the BACH2 protein (arrow).

Anti-BACH2 Antibody (aa282-312, FITC) - LS-C212912 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa282-312, Azide-free, HRP) - LS-C212913 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa282-312, PE) - LS-C212914 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa822-849) - LS-C319750 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (aa282-312) - LS-C319749 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BACH2 Antibody (N-Terminus) - LS-C209338 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot of Rabbit anti-Bach2 antibody. Lane 1: 293T cell lysates overexpressing Bach2-Flag. Lane 2: 293T cell lysates. Load: 20 ug per lane. Primary antibody: Bach-2 antibody at 1:1000 for overnight at 4 degrees C. Secondary antibody: rabbit HRP secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4 degrees C. Predicted/Observed size: 91.7 kDa, ~130 kDa for Bach2. Other band(s): none.

Anti-BACH2 Antibody (aa815-841) - LS-C156726 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BACH2 Antibody western blot of MDA-MB435 cell line lysates (35 ug/lane). The BACH2 antibody detected the BACH2 protein (arrow).

Anti-BACH2 Antibody (C-Terminus) IHC-plus™ - LS-B3533 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BACH2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3533 concentration 2.5 ug/ml.

Anti-BACH2 Antibody (aa822-849, APC) - LS-C212904 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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