SLC9A3

Gene Symbol SLC9A3
Entrez Gene 6550
Alt Symbol NHE3
Species Human
Gene Type protein-coding
Description solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Other Description NHE-3|Na(+)/H(+) exchanger 3|sodium/hydrogen exchanger 3|solute carrier family 9 (sodium/hydrogen exchanger)|solute carrier family 9 (sodium/hydrogen exchanger), member 3|solute carrier family 9 member 3
Swissprots Q3MIW3 B7ZKR2 E9PF67 P48764
Accessions AAM53435 EAW51006 EAW51007 P48764 BC011555 BC101669 AAI01670 BC101671 AAI01672 BC143328 AAI43329 BP270851 S83545 AAB50819 U28043 AAB48990 XM_011514095 XP_011512397 XM_011514096 XP_011512398 XM_011514097 XP_011512399 XM_011514098 XP_011512400 NM_001284351 NP_001271280 NM_004174 NP_004165
Function Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:19088451}; Multi-pass membrane protein {ECO:0000269|PubMed:19088451}. Note=In intestinal epithelial cells, localizes to the ileal brush border. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane.
Top Pathways Proximal tubule bicarbonate reclamation, Protein digestion and absorption, Bile secretion, Mineral absorption

NHE-3 (C-20)-R - sc-16103-R from Santa Cruz Biotechnology

Prices $61.00
Sizes 100 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
NHE-3 (C-20): sc-16103. Western blot analysis of NHE-3 expression in MDCK whole cell lysate.

NHE-3 (D-18) - sc-31384 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NHE-3 (H-170) - sc-28757 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NHE-3 (H-170): sc-28757. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells.

NHE-3 (53) - sc-136368 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NHE-3 (53): sc-136368. Western blot analysis of NHE-3 expression in 293 whole cell lysate.

NHE-3 (V-16) - sc-31382 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NHE-3 (V-16): sc-31382. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing membrane and cytoplasmic staining of glandular cells.

p-NHE-3 (10A8) - sc-53961 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of NHE-3 phosphorylation in non-transfected: sc-110760 (A,D), untreated mouse NHE-3 transfected: sc-179002 (B,E) and lambda protein phosphatase (sc-200312A) treated mouse NHE-3 transfected: sc-179002 (C,F) 293 whole cell lysates. Antibodies tested include p-NHE-3 (10A8): sc-53961 (A,B,C) and NHE-3 (53): sc-136368 (D,E,F).

p-NHE-3 (14D5) - sc-53962 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of NHE-3 phosphorylation in non-transfected: sc-110760 (A,D), untreated mouse NHE-3 transfected: sc-179002 (B,E) and lambda protein phosphatase (sc-200312A) treated mouse NHE-3 transfected: sc-179002 (C,F) 293 whole cell lysates. Antibodies tested include p-NHE-3 (14D5): sc-53962 (A,B,C) and NHE-3 (53): sc-136368 (D,E,F).

Anti-Sodium / Hydrogen Exchanger 3 (phospho S552) antibody [14D5] - ab72729 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 14D5
Anti-Sodium / Hydrogen Exchanger 3 (phospho S552) antibody [14D5] (ab72729) at 5 µg/ml + human kidney lysate

Anti-Sodium / Hydrogen Exchanger 3 antibody - ab186968 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-Sodium / Hydrogen Exchanger 3 antibody - ab101817 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Sodium / Hydrogen Exchanger 3 antibody - ab90630 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC9A3 / NHE3 Antibody (C-Terminus) - LS-C16758 from LifeSpan Bioscience

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC9A3 / NHE3 Antibody (C-Terminus) - LS-C16762 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SLC9A3 / NHE3 Antibody (C-Terminus) - LS-C16766 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC9A3 / NHE3 Antibody (C-Terminus) - LS-C132155 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC9A3 / NHE3 Antibody (C-Terminus) - LS-C122201 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SLC9A3 / NHE3 Antibody (C-Terminus, clone 19F5, Biotin) - LS-C141740 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 19F5

Anti-SLC9A3 / NHE3 Antibody (C-Terminus, clone 19F5, DY650) - LS-C141741 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 19F5

Anti-SLC9A3 / NHE3 Antibody (C-Terminus, clone 19F5, DY488) - LS-C141742 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 19F5

Anti-SLC9A3 / NHE3 Antibody (C-Terminus, clone 19F5, HRP) - LS-C141743 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 19F5

Anti-SLC9A3 / NHE3 Antibody (C-Terminus, clone 19F5, DY550) - LS-C141744 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 19F5

Anti-SLC9A3 / NHE3 Antibody (phospho-Ser605, clone 10A8) - LS-C141778 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10A8

Anti-SLC9A3 / NHE3 Antibody (phospho-Ser605, clone 10A8, Biotin) - LS-C141779 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10A8

Anti-SLC9A3 / NHE3 Antibody (phospho-Ser605, clone 10A8, DY650) - LS-C141780 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10A8

Anti-SLC9A3 / NHE3 Antibody (phospho-Ser605, clone 10A8, DY488) - LS-C141781 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 10A8
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